3-Epidehydrotumulosic acidCAS# 167775-54-4 |
- Dehydrotumulosic acid
Catalog No.:BCN3740
CAS No.:6754-16-1
Quality Control & MSDS
Number of papers citing our products
Chemical structure
3D structure
| Cas No. | 167775-54-4 | SDF | Download SDF |
| PubChem ID | 10005581 | Appearance | Powder |
| Formula | C31H48O4 | M.Wt | 484.7 |
| Type of Compound | Triterpenoids | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| Chemical Name | (2R)-2-[(3R,5R,10S,13R,14R,16R,17R)-3,16-dihydroxy-4,4,10,13,14-pentamethyl-2,3,5,6,12,15,16,17-octahydro-1H-cyclopenta[a]phenanthren-17-yl]-6-methyl-5-methylideneheptanoic acid | ||
| SMILES | CC(C)C(=C)CCC(C1C(CC2(C1(CC=C3C2=CCC4C3(CCC(C4(C)C)O)C)C)C)O)C(=O)O | ||
| Standard InChIKey | LADJWZMBZBVBSB-HSGZZQKSSA-N | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
||
| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
||
| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
| Description | 1. 3-Epidehydrotumulosic acid has inhibitory activity against AAPH-induced lysis of red blood cells. |
3-Epidehydrotumulosic acid Dilution Calculator
3-Epidehydrotumulosic acid Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 2.0631 mL | 10.3157 mL | 20.6313 mL | 41.2626 mL | 51.5783 mL |
| 5 mM | 0.4126 mL | 2.0631 mL | 4.1263 mL | 8.2525 mL | 10.3157 mL |
| 10 mM | 0.2063 mL | 1.0316 mL | 2.0631 mL | 4.1263 mL | 5.1578 mL |
| 50 mM | 0.0413 mL | 0.2063 mL | 0.4126 mL | 0.8253 mL | 1.0316 mL |
| 100 mM | 0.0206 mL | 0.1032 mL | 0.2063 mL | 0.4126 mL | 0.5158 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
Calcutta University
University of Minnesota
University of Maryland School of Medicine
University of Illinois at Chicago
The Ohio State University
University of Zurich
Harvard University
Colorado State University
Auburn University
Yale University
Worcester Polytechnic Institute
Washington State University
Stanford University
University of Leipzig
Universidade da Beira Interior
The Institute of Cancer Research
Heidelberg University
University of Amsterdam
University of Auckland
TsingHua University
The University of Michigan
Miami University
DRURY University
Jilin University
Fudan University
Wuhan University
Sun Yat-sen University
Universite de Paris
Deemed University
Auckland University
The University of Tokyo
Korea University
- Ornidazole
Catalog No.:BCC4815
CAS No.:16773-42-5
- RS 39604 hydrochloride
Catalog No.:BCC5694
CAS No.:167710-87-4
- Boc-Asp(OtBu)-OH
Catalog No.:BCC3368
CAS No.:1676-90-0
- Z-Ser(tBu)-OH
Catalog No.:BCC2740
CAS No.:1676-75-1
- H-Glu(OBzl)-OH
Catalog No.:BCC2926
CAS No.:1676-73-9
- Benoxafos
Catalog No.:BCC5470
CAS No.:16759-59-4
- 11-Hydroxy-12-methoxyabietatriene
Catalog No.:BCN3253
CAS No.:16755-54-7
- PD-1/PD-L1 inhibitor 2
Catalog No.:BCC6520
CAS No.:1675203-84-5
- BADGE
Catalog No.:BCC7022
CAS No.:1675-54-3
- LY335979 (Zosuquidar 3HCL)
Catalog No.:BCC3878
CAS No.:167465-36-3
- Sophoracarpan B
Catalog No.:BCN6979
CAS No.:1674359-84-2
- Sophoracarpan A
Catalog No.:BCN6980
CAS No.:1674359-82-0
- PD98059
Catalog No.:BCC1098
CAS No.:167869-21-8
- Rubelloside B
Catalog No.:BCN1099
CAS No.:167875-39-0
- Wilforol A
Catalog No.:BCN3064
CAS No.:167882-66-8
- ent-Kaurane-16beta,19,20-triol
Catalog No.:BCN7654
CAS No.:167898-32-0
- 2,5-Bis(4-diethylaminophenyl)-1,3,4-oxadiazole
Catalog No.:BCC8502
CAS No.:1679-98-7
- Crassanine
Catalog No.:BCN4073
CAS No.:16790-92-4
- 19(S)-Hydroxyconopharyngine
Catalog No.:BCN3976
CAS No.:16790-93-5
- Taxachitriene A
Catalog No.:BCN6952
CAS No.:167906-74-3
- Taxachitriene B
Catalog No.:BCN6951
CAS No.:167906-75-4
- Stigmasta-4,22-diene-3beta,6beta-diol
Catalog No.:BCN1533
CAS No.:167958-89-6
- Otophylloside B 4'''-O-beta-D-oleandropyranoside
Catalog No.:BCN7512
CAS No.:168001-54-5
- Triptonine B
Catalog No.:BCN3095
CAS No.:168009-85-6
Inhibition of tumor-promoting effects by poricoic acids G and H and other lanostane-type triterpenes and cytotoxic activity of poricoic acids A and G from Poria cocos.[Pubmed:11975480]
J Nat Prod. 2002 Apr;65(4):462-5.
The structures of two novel 3,4-seco-lanostane-type triterpenes isolated from the sclerotium of Poria cocos were established to be 16alpha-hydroxy-3,4-seco-lanosta-4(28),8,24-triene-3,21-dioic acid (1; poricoic acid G) and 16alpha-hydroxy-3,4-seco-24-methyllanosta-4(28),8,24(24(1))-triene-3,21-dioic acid (2; poricoic acid H) on the basis of spectroscopic methods. These two, and eight other known compounds isolated from the sclerotium, poricoic acid B (3), poricoic acid A (4), tumulosic acid (5), dehydrotumulosic acid (6), 3-Epidehydrotumulosic acid (7), polyporenic acid C (8), 25-hydroxy-3-Epidehydrotumulosic acid (9), and dehydroabietic acid methyl ester (10), showed potent inhibitory effects on Epstein-Barr virus early antigen (EBV-EA) activation induced by the tumor promoter 12-O-tetradecanoylphorbol-13-acetate (TPA). Evaluation of the cytotoxicity of compounds 1 and 4 against human cancer cell lines revealed that 1 was significantly cytotoxic to leukemia HL-60 cells [GI(50) (concentration that yields 50% growth) value 39.3 nM], although it showed only moderate cytotoxicity to the other cells. Compound 4 exhibited moderate cytotoxicity to all of the cancer cell lines tested.
Inhibitory effects of triterpenes isolated from Hoelen on free radical-induced lysis of red blood cells.[Pubmed:12601680]
Phytother Res. 2003 Feb;17(2):160-2.
Hoelen, sclederma of Poria cocos Wolf, has long been used as a sedative and diuretic in traditional medicine. Formerly, we demonstrated that Hoelen in vitro protects red blood cells from AAPH-induced hemolysis. In this study, tests were carried out to identify the main ingredient of Hoelen that has the scavenging effect on free-radicals. Triterpene carboxylic acids isolated from the methanol extract of Hoelen, i.e. pachymic acid, polyporenic acid, 3-Epidehydrotumulosic acid, 3beta-hydroxylanosta-7,9(11), 24-trien-21-oic acid and 3-o-acetyl-16 alpha -hydroxytrametenolic acid, were found to have inhibitory activities against AAPH-induced lysis of red blood cells.
