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2',4'-Dihydroxy-7-methoxy-8-prenylflavan

CAS# 331954-16-6

2',4'-Dihydroxy-7-methoxy-8-prenylflavan

Catalog No. BCN6844----Order now to get a substantial discount!

Product Name & Size Price Stock
2',4'-Dihydroxy-7-methoxy-8-prenylflavan:5mg Please Inquire In Stock
2',4'-Dihydroxy-7-methoxy-8-prenylflavan:10mg Please Inquire In Stock
2',4'-Dihydroxy-7-methoxy-8-prenylflavan:20mg Please Inquire In Stock
2',4'-Dihydroxy-7-methoxy-8-prenylflavan:50mg Please Inquire In Stock

Quality Control of 2',4'-Dihydroxy-7-methoxy-8-prenylflavan

Number of papers citing our products

Chemical structure

2',4'-Dihydroxy-7-methoxy-8-prenylflavan

3D structure

Chemical Properties of 2',4'-Dihydroxy-7-methoxy-8-prenylflavan

Cas No. 331954-16-6 SDF Download SDF
PubChem ID 10132047 Appearance Powder
Formula C21H24O4 M.Wt 340.42
Type of Compound Flavonoids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name 4-[(2S)-7-methoxy-8-(3-methylbut-2-enyl)-3,4-dihydro-2H-chromen-2-yl]benzene-1,3-diol
SMILES CC(=CCC1=C(C=CC2=C1OC(CC2)C3=C(C=C(C=C3)O)O)OC)C
Standard InChIKey OAUAVKGFNHNNGR-FQEVSTJZSA-N
Standard InChI InChI=1S/C21H24O4/c1-13(2)4-8-17-19(24-3)10-5-14-6-11-20(25-21(14)17)16-9-7-15(22)12-18(16)23/h4-5,7,9-10,12,20,22-23H,6,8,11H2,1-3H3/t20-/m0/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of 2',4'-Dihydroxy-7-methoxy-8-prenylflavan

The

Biological Activity of 2',4'-Dihydroxy-7-methoxy-8-prenylflavan

In vitro

Chemical constituents of Morus alba L. and their inhibitory effect on 3T3-L1 preadipocyte proliferation and differentiation.[Reference: WebLink]

Fitoterapia, 2014, 98:222-227.

Mulberry leaf, an important traditional Chinese medicine, possesses many biological activities, including effects of anti-obesity. However, which constituents of mulberry leaf are responsible for its anti-adipogenic action is unclear.
METHODS AND RESULTS:
This study primarily investigated the chemical constituents from mulberry leaf and their bioactivity on the proliferation and differentiation of 3T3-L1 preadipocytes. A new flavane derivative, (2S)-4′-hydroxy-7-methoxy-8-prenylflavan (2',4'-Dihydroxy-7-methoxy-8-prenylflavan,1), together with twelve known compounds including three flavanes (2–4), three chalcones (5–7), two flavones (8–9), two benzofurans (10–11) and two coumarin (12–13) was isolated from mulberry leaf. The structure of the new compound was elucidated by various spectroscopic methods including UV, HR-ESI-MS, 1H and 13C NMR and CD.
CONCLUSIONS:
The results of activity screening showed that compound 2, 6 and 7 inhibited the proliferation and differentiation of 3T3-L1 preadipocytes.

2',4'-Dihydroxy-7-methoxy-8-prenylflavan Dilution Calculator

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2',4'-Dihydroxy-7-methoxy-8-prenylflavan Molarity Calculator

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Preparing Stock Solutions of 2',4'-Dihydroxy-7-methoxy-8-prenylflavan

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.9375 mL 14.6877 mL 29.3755 mL 58.751 mL 73.4387 mL
5 mM 0.5875 mL 2.9375 mL 5.8751 mL 11.7502 mL 14.6877 mL
10 mM 0.2938 mL 1.4688 mL 2.9375 mL 5.8751 mL 7.3439 mL
50 mM 0.0588 mL 0.2938 mL 0.5875 mL 1.175 mL 1.4688 mL
100 mM 0.0294 mL 0.1469 mL 0.2938 mL 0.5875 mL 0.7344 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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