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1-Methoxyberberine

CAS# 29133-52-6

1-Methoxyberberine

Catalog No. BCN7373----Order now to get a substantial discount!

Product Name & Size Price Stock
1-Methoxyberberine:5mg Please Inquire In Stock
1-Methoxyberberine:10mg Please Inquire In Stock
1-Methoxyberberine:20mg Please Inquire In Stock
1-Methoxyberberine:50mg Please Inquire In Stock

Quality Control of 1-Methoxyberberine

Number of papers citing our products

Chemical structure

1-Methoxyberberine

3D structure

Chemical Properties of 1-Methoxyberberine

Cas No. 29133-52-6 SDF Download SDF
PubChem ID 3082297 Appearance Powder
Formula C21H20NO5 M.Wt 366.4
Type of Compound Alkaloids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
SMILES COC1=C(C2=C[N+]3=C(C=C2C=C1)C4=C(C5=C(C=C4CC3)OCO5)OC)OC.[Cl-]
Standard InChIKey IBMPNZBFNHPRMY-UHFFFAOYSA-M
Standard InChI InChI=1S/C21H20NO5.ClH/c1-23-16-5-4-12-8-15-18-13(6-7-22(15)10-14(12)19(16)24-2)9-17-20(21(18)25-3)27-11-26-17;/h4-5,8-10H,6-7,11H2,1-3H3;1H/q+1;/p-1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of 1-Methoxyberberine

The herbs of Corydalis longipes.

Biological Activity of 1-Methoxyberberine

Description1. 1-Methoxyberberine chloride is a potential antifungal agent.
TargetsAntifection

1-Methoxyberberine Dilution Calculator

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1-Methoxyberberine Molarity Calculator

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Preparing Stock Solutions of 1-Methoxyberberine

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.7293 mL 13.6463 mL 27.2926 mL 54.5852 mL 68.2314 mL
5 mM 0.5459 mL 2.7293 mL 5.4585 mL 10.917 mL 13.6463 mL
10 mM 0.2729 mL 1.3646 mL 2.7293 mL 5.4585 mL 6.8231 mL
50 mM 0.0546 mL 0.2729 mL 0.5459 mL 1.0917 mL 1.3646 mL
100 mM 0.0273 mL 0.1365 mL 0.2729 mL 0.5459 mL 0.6823 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on 1-Methoxyberberine

Two plant alkaloids isolated from Corydalis longipes as potential antifungal agents.[Pubmed:14976716]

Folia Microbiol (Praha). 2003;48(5):605-9.

The alkaloids N-methylhydrasteine hydroxylactam and 1-Methoxyberberine chloride were isolated from Corydalis longipes. Both alkaloids showed high efficacy individually (in concentration of 50-150 ppm) and also in a 1:1 mixture against spore germination of some fungi, viz. Alternaria alternata, A. brassicae, Curvularia maculans, Curvularia sp., Colletotrichum gloeosporioides, Colletotrichum sp., Helminthosporium speciferum, H. pennisetti, Helminthosporium sp., and Ustilago cynodontis. The antifungal effect of single compounds was dose-dependent. If the mutual ratio of the two components in the mixture was changed from 1:1 to a major content of any of the two compounds, the inhibitory effect on spore germination decreased.

New alkaloids from Corydalis species.[Pubmed:19235025]

Nat Prod Res. 2009;23(3):250-5.

A new alkaloid, chaerophylline (1), together with known alkaloids (-)-corypalmine, berberine chloride, (-)-isocorypalmine, (-)-corydalmine and (+)-bicuculline have been isolated from the crude base fraction of Corydalis chaerophylla. The crude base fractions of Corydalis longipes gave a new alkaloid, longicine (4), together with known alkaloids (+/-)-alpha-hydrastine, (+/-)-beta-hydrastine, N-methylhydrasteine hydroxylactam, 1-Methoxyberberine chloride and berberinium hydroxide. These alkaloids are reported for the first time from the above species and their structures were established by chemical and spectroscopic evidence.

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