Products with Pro-apoptotic bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN2934 | Terrestrosin D |
| 1. Terrestrosin D can induce apoptotic cell death and inhibit angiogenesis in xenograft tumor cells, cell cycle arrest and induction of apoptosis in cancer cells and endothelial cells might be plausible mechanisms of actions for the observed antitumor and antiangiogenic activities of terrestrosin D. | |
| BCN2948 | Fucoxanthin |
| Fucoxanthin shows anti-obesity, antioxidant, anti-inflammatory, chemopreventive and/or chemotherapeutic effects. Dietary combination of fucoxanthin and fish oil attenuates the weight gain of white adipose tissue and decreases blood glucose in obese/diabetic KK-Ay mice. Fucoxanthin suppresses the inflammation of endotoxin-induced uveitis by blocking the iNOS and COX-2 protein expression and its anti-inflammatory effect on eye is comparable with the effect of predinisolone used in similar doses. | |
| BCN2951 | Sodium Dichloroacetate |
| Sodium dichloroacetate is a drug with potential for treating patients with stroke and head injury. Sodium dichloroacetate exhibits anti-leukemic activity in B-chronic lymphocytic leukemia (B-CLL) and synergizes with the p53 activator Nutlin-3; it is cytoprotective to some colorectal cancer cells under hypoxic conditions. | |
| BCN2990 | Eurycomanone |
| Eurycomanone has anti-cancer activity, it is cytotoxic on HepG2 cells by inducing apoptosis through the up-regulation of p53 and Bax, and down-regulation of Bcl-2. | |
| BCN2997 | Desmethylxanthohumol |
| 1. Xanthohumol shows the highest inhibition against cholesteryl ester transfer protein (CETP) from screening of natural products in various plants; prenyl group and chalcone structure of xanthohumol are responsible for the CETP inhibitory activity. | |
