Products with Pro-apoptotic bioactivity

Cat.No. Product Name
BCN3115 Delphinidin-3-O-rutinoside chloride
1. Delphinidin-3-O-rutinoside chloride has antioxidant activity.
BCN3132 Chamaejasmine
1. Chamaejasmine inhibits Bcl-2 expression and induces Bax expression to desintegrate the outer mitochondrial membrane and causes cytochrome c release. 2. Chamaejasmine could be a candidate drug for osteosarcoma and breast cancer chemoprevention, induces apoptosis in MG63 and HEp-2 cells by Akt inactivation and dephosphorylation of BAD.
BCN3231 Ponicidin
1. Ponicidin has immunoregulatory and anti-inflammatory functions . 2. Ponicidin has anti-viral function especially in the upper respiratory tract infection. 3. Ponicidin has anti-leukemia activity, by inducing apoptosis, downregulation of survivin as well as Bcl-2 expressions. 4. Ponicidin has anti-cancer activity against gastric carcinoma and lung cancer; can inhibit growth and induce apoptosis of gastric carcinoma cell line MKN28, via the signaling pathway regulated by Janus kinase 2 (JAK2) and signal transducers and activators of transcription 3 (STAT3).
BCN3234 Effusanin E
1. Effusanin E shows antibacterial activity. 2. Effusanin E significantly inhibits cell proliferation and induces apoptosis in NPC cells by suppressing p50/p65 proteins to down-regulate COX-2 expression .
BCN3276 Kuguaglycoside C
1. Kuguaglycoside C induces caspase-independent cell death, and is involved, at least in part, in the mechanism underlying cell necroptosis.

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