Products with Inhibitors bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN1805 | 4-Hydroxybenzylamine |
| 1. 4-Hydroxybenzaldehyde derivatives are inhibitors for GABA transaminase (GABA-T) and succinic semialdehyde dehydrogenase (SSADH), 4-Hydroxybenzylamine also shows the competitive inhibition on GABA-T with respect to GABA. | |
| BCN1808 | Lavendustin A |
| 1. Lavendustin A and hormothamnione exhibit cytotoxic effects on tumor cell lines. 2. Lavendustin A is a potent tyrosine kinase inhibitor of the epidermal growth factor (EGF) receptor, and an angiogenesis inhibitor. 3. Lavendustin A is a hyperbolic mixed-type inhibitor with respect to both ATP and the peptide substrate, with a major effect on the binding affinities for both substrates. 4. Lavendustin A at 0.1 nM-1 microM causes a concave-shaped inhibition of the insulin release stimulated by 7 mM glucose, the inhibitory effect can be overcomed by higher concentrations of glucose. | |
| BCN1809 | Lavendustin B |
| 1. Lavendustin B is an inhibitor of HIV-1 integrase (IN) interaction with its cognate cellular cofactor, lens epithelium-derived growth factor (LEDGF/p75). | |
| BCN1821 | Aburatubolactam A |
| 1. Aburatubolactam A is an inhibitor of superoxide anion generation. 2. Aburatubolactam A has demonstrated cytotoxic activity against P388 murine leukemia cell lines (IC50 = 26 ug/mL) and inhibits TPA-induced superoxide anion generation by human neutrophils; enhanced levels of superoxide anion is thought to be closely related to inflammation, cancer, and aging. | |
| BCN1822 | Aflastatin A |
| 1. Aflastatin A is a specific inhibitor of aflatoxin production by Aspergillus parasiticus, inhibits a very early step in aflatoxin biosynthesis prior to the transcription of aflR and can influence glucose metabolism in the fungus. 2. Aflastatin A inhibits an early step in melanin production, which suppresses the expression of PKS1. 3. Aflastatin A exhibits antimicrobial activity against some bacteria, yeasts and fungi. 4. Aflastatin A has antitumor activity. | |
