Products with Cytotoxic bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN5184 | Erythristemine |
| 1. (+)-Erythristemine shows moderate toxicity to brine shrimp (LC50 23 ppm) and moderate (IC50=86microg/ml) radical scavenging properties against stable 2,2-diphenyl-1-picrylhy--drazyl (DPPH) radical. | |
| BCN5210 | Effusanin A |
| 1. Effusanin A exhibits DNA-damaging activity in assay which employed DNA-repair deficient (RAD 52Y) and repair proficient (RAD +) yeast strains. 2. Effusanin A has antibacterial activity. 3. Effusanin A shows inhibitory effects on DU145 cells with IC50 value of 3.16 microM, and LoVo cells with IC50 value of 3.02 microM. | |
| BCN5212 | 3,4,5-Trimethoxycinnamyl alcohol |
| 1. 3,4,5-Trimethoxycinnamyl alcohol shows significant antimicrobial and cytotoxic activities. | |
| BCN5216 | Centrolobol |
| 1. (-)-Centrolobol has antifibrotic activity, it can significantly inhibit the proliferation of HSC-T6 cells in a dose-dependent manner. 2. Centrolobol exhibits strong cytotoxic activity against KB cell line. | |
| BCN5232 | Isobavachin |
| Isobavachin can stimulate osteoblasts proliferation and differentiation; it also can facilitate mouse embryonic stem cells differentiating into neuronal cells, the mechanism involved protein prenylation and, subsequently, phos-ERK activation and the phos-p38 off pathway. Isobavachin possesses estrogen-like activity in MCF-7/BOS cells, it can significantly stimulate the proliferation of MCF-7/BOS cells in a dose-dependent manner. Isobavachin has cytotoxic effects on H4IIE hepatoma and metabolically poorly active C6 glioma cells. | |
