Products with Anticancer bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN4454 | Chrysothol |
| 1. Chrysothol shows strong antimicrobial activities (MICs=50-100 ug/ml) against enterobacteria E. coli and S. enteritidis. 2. Chrysothol shows anti-cancer activity against human breast cancer cells. | |
| BCN4464 | Viscidulin III |
| Viscidulin III (17.4 microM), wogonin (17.4 microM) and luteolin (18.4 microM) were more effective than baicalein (23.0 microM) which reportedly inhibits the proliferation of some cancer cell lines. | |
| BCN4470 | Scopoletin |
| Scopoletin exhibits antifungal, anti-allergic, anti-aging, and hypouricemic activities, it exerts anti-RA action probably through suppressing IL-6 production from fibroblast-like synoviocytes via MAPK/PKC/CREB pathways. Scopoletin can ameliorate alcohol-induced hepatic lipid accumulation by modulating AMPK-SREBP pathway-mediated lipogenesis in mice fed a high-fat diet. | |
| BCN4480 | Karavilagenin D |
| 1. Karavilagenin D exhibits inhibitory effects on skin-tumor promotion in an in vivo two-stage mouse skin carcinogenesis test based on 7,12-dimethylbenz[a]anthracene (DMBA) as initiator, and with TPA as a promoter. 2. Karavilagenin D exhibits inhibition effect against human cancer cell lines. | |
| BCN4494 | Sappanchalcone |
| 1. Sappanchalcone has cytoprotective effect. 2. Sappanchalcone blocks cell cycle progression in the G2/M phase, brazilin inhibited TNFα/NF-κB signaling. 3. Sappanchalcone has anti-inflammatory effect, could be used as an anti-inflammatory and bone-protective agent during the treatment of rheumatoid arthritis. 4. Sappanchalcone suppresses oral cancer cell growth and induces apoptosis through the activation of p53-dependent mitochondrial, p38, ERK, JNK, and NF-κB signaling, could potentially used to treat periodontal, pulpal , periapical inflammatory lesion and oral cancer. 5. Sappanchalcone possesses the most potent effect against allergic reaction in basophilic leukemic (RBL-2H3) cells with an inhibitory concentration (IC50) value of 7.6 uM, it may have anti-allergic activity. 6. Sappanchalcone shows xanthine oxidase inhibitory activity, is a xanthine oxidase inhibitor. | |
