Products with Anti-proliferation bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN2942 | Zingiberen newsaponin |
| 1. Zingiberensis newsaponin I exhibits induction effect on platelet aggregation. 2. Zingiberensis saponin can inhibit the proliferation of a panel of established human and murine cancer cell lines in vitro, its proliferation inhibitory effect is associated with its apoptosis-inducing effect by activation of caspase-3 and caspase-9 and specific proteolytic cleavage of poly (ADP-ribose) polymerase, thus, zingiberensis saponin is an effective natural agent for cancer therapy. | |
| BCN2948 | Fucoxanthin |
| Fucoxanthin shows anti-obesity, antioxidant, anti-inflammatory, chemopreventive and/or chemotherapeutic effects. Dietary combination of fucoxanthin and fish oil attenuates the weight gain of white adipose tissue and decreases blood glucose in obese/diabetic KK-Ay mice. Fucoxanthin suppresses the inflammation of endotoxin-induced uveitis by blocking the iNOS and COX-2 protein expression and its anti-inflammatory effect on eye is comparable with the effect of predinisolone used in similar doses. | |
| BCN2981 | Beta-Elemonic acid |
| 1. Beta-Elemonic acid exhibits anti-inflammatory effects. 2. Beta-Elemonic acid inhibits proliferation by inducing hypoploid cells and cell apoptosis, the anticancer effects of beta-Elemonic acid are related to the MAPK signaling pathway, ROS activation and glutathione depletion in human A549 lung cancer cells. 3. Beta-Elemonic acid exhibits prolyl endopeptidase inhibitory activities. | |
| BCN2990 | Eurycomanone |
| Eurycomanone has anti-cancer activity, it is cytotoxic on HepG2 cells by inducing apoptosis through the up-regulation of p53 and Bax, and down-regulation of Bcl-2. | |
| BCN2997 | Desmethylxanthohumol |
| 1. Xanthohumol shows the highest inhibition against cholesteryl ester transfer protein (CETP) from screening of natural products in various plants; prenyl group and chalcone structure of xanthohumol are responsible for the CETP inhibitory activity. | |
