Products with Anti-multidrug resistance bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN4963 | Lathyrol |
| Lathyrol diterpenes is a modulator of P-glycoprotein dependent multidrug resistance, and is used for cancer treatment. | |
| BCN5074 | Ecdysterone 2,3:20,22-diacetonide |
| 1. Due to the multi-drug resistance reversal activity of the less polar ecdysteroids, several new products( including 20-hydroxyecdysone,20-hydroxyecdysone 2,3;20,22-diacetonide) are promising for being tested against various cancer cell lines. | |
| BCN5382 | Epoxylathyrol |
| 1. Epoxylathyrol derivatives have modulation of ABCB1-mediated multidrug resistance in human colon adenocarcinoma and mouse T-Lymphoma cells. | |
| BCN5393 | Cepharanthine |
| Cepharanthine has anti-plasmodial, anti-tumor , anti-inflammatory, antiallergic, antioxidant, and immunomodulatory activities in vivo, and it is a highly potent inhibitor of HIV-1 replication in a chronically infected monocytic cell line. Cepharanthine inhibits the HIV-1 entry process by reducing plasma membrane fluidity, and the plasma membrane is therefore an identical target to prevent viral infection. | |
| BCN5415 | Isobavachalcone |
| Isobavachalcone has anti-cancer, anthelmintic, antibacterial, aphrodisiac, anti-inflammatory, astringent and antiplatelet activities, Isobavachalcone can induce apoptotic cell death in neuroblastoma via the mitochondrial pathway; it can significantly inhibit both oligomerization and fibrillization of Aβ42; it can suppress inducible nitric oxide synthase (iNOS) expression induced by macrophage-activating lipopeptide 2-kDa, polyriboinosinic polyribocytidylic acid, or lipopolysaccharide. | |
