Products with Anti-melanogenic bioactivity

Cat.No. Product Name
BCN2996 Sappanone A
1. Sappanone A is the first homoisoflavanone to be discovered with melanogenesis inhibitory activity. 2. Sappanone A exerts its anti-inflammatory effect by modulating the Nrf2 and NF-κB pathways, and may be a valuable compound to prevent or treat inflammatory diseases.
BCN3288 Chlorophorin
1. Chlorophorin shows high anti-protozoal activity with an MIC of 0.25 microg/ml. 2. Chlorophorin can strongly inhibit mushroom tyrosinase activity with IC50 values of 2.5 ± 0.408 uM. 3. Chlorophorin can reduce tyrosinase activity and inhibit α-melanocyte-stimulating hormone-induced melanin production in B16F10 melanoma cells.
BCN3290 Albanin A
1. Albanin A shows mushroom tyrosinase inhibitory activity, the IC50 value is 463 uM. 2. In melanin formation inhibition on B16 melanoma cells, the IC50 of albanin A is 40.1 uM.
BCN3382 Gnetol
1. Gnetol has a strong inhibitory effect on murine tyrosinase activity. 2. Gnetol significantly suppresses melanin biosynthesis in murine B16 melanoma cells. 3. Gnetol has the IC(50) value of 1.3 uM towards butyrylcholinesterase and shows a reversible and competitive inhibition in the kinetic study. 4. Gnetol is active in the inhibition of arachidonic acid (AA)-induced platelet aggregation.
BCN3447 Kurarinol
1. Kurarinol is a potent inhibitor of sortase A, with an IC50 value of 107.7 ± 6.6 μM. 2. Kurarinol has extremely strong tyrosinase inhibitory activity, exerts varying degrees of inhibition on tyrosinase-dependent melanin biosynthesis, is a candidate as skin-whitening agents.

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