Products with Anti-leishmanial bioactivity

Cat.No. Product Name
BCN4101 Tagitinin F
1. Tagitinin F shows in vitro leishmanicidal activities against Leishmania braziliensis promastigotes and amastigotes. 2. Tagitinin F possesses antileukemic activity.
BCN4143 Neridienone B
1. Neridienone B has significant effects on calcein accumulation. 2. Neridienone exhibits significant leishmanicidal activity against amastigotes of L. mexicana.
BCN4198 Phebalosin
1. Phebalosin displays 50% effective concentrations (EC(50)) of 14.1 microg/mL against axenic amastigote forms of Leishmania panamensis. 2. Phebalosin displays cytotoxicity (IC(50)) at concentrations of 20.7 microg/mL on human promonocytic U-937 cells.
BCN4315 Quassin
1. Quassin exhibits P. falciparum inhibitory activity (IC50=0.06 micro g/ml, 0.15 micro M). 2. Quassin can significantly increase red blood cell count, pack cell volume and haemoglobin concentration, suggests that it possesses anti-anaemic property. 3. Quassin has female anti-fertility properties, possibly acting via inhibition of estrogen secretion. 4. Quassin alters the immunological patterns of murine macrophages through generation of nitric oxide to exert antileishmanial activity.
BCN4737 Diacetylpiptocarphol
1. Diacetylpiptocarphol shows antileishmanial activity against three stages of Leishmania infantum.

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