Products with Anti-leishmanial bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN5381 | Beta-Hederin |
| 1. Beta-Hederin has antileishmanial activity. 2. Beta-Hederin has apoptotic effect on breast cancer cells, it could be a promising candidate for chemotherapy of breast cancer. | |
| BCN5459 | Nerolidol |
| Nerolidol, a sesquiterpene used as a food-flavoring agent and currently under testing as a skin penetration enhancer for the transdermal delivery of therapeutic drugs. Nerolidol shows anti-cancer, sedative, antiulcer, antifungal, and antifeeding effects. Nerolidol can inhibit the growth of Leishmania amazonensis, L. braziliensis, and L. chagasi promastigotes and L. amazonensis amastigotes with in vitro 50% inhibitory concentrations of 85, 74, 75, and 67 uM, respectively. | |
| BCN5462 | Medioresinol |
| 1. Medioresinol possesses a lesishmanicidal activity and cardiovascular disease risk reduction. 2.(+)-Medioresinol has anti-bacterial, antifungal and anti-biofilm activities. 3. Medioresinol has antioxidative activity. 4. Medioresinol has antiamyloidogenic activity via reduction in the amount of β-secretase, it is a potentially valuable antiamyloidogenic agent for the prevention and treatment of Alzheimer disease. | |
| BCN5568 | Isopimpinellin |
| Isopimpinellin has chemopreventive effects, it effectively inhibits mouse COH activity (IC50 values 19-40 microM).Isopimpinellin is a new inhibitor against the Leishmania APRT enzyme. | |
| BCN5614 | Niranthin |
| 1. Niranthin exhibits anti-hepatitis B virus activity both in vitro and in vivo. 2. Niranthin exhibits antiinflammatory and antiallodynic actions which are probably mediated through its direct antagonistic action on the PAF receptor binding sites. 3. Niranthin is a potent anti-leishmanial agent, inhibits the relaxation activity of heterodimeric type IB topoisomerase of L. donovani and acts as a non-competitive inhibitor interacting with both subunits of the enzyme. | |
