Products with Anti-inflammatory bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN2390 | Brucine |
| Brucine has anti-cncer activity, it can treat hepatocellular carcinoma (HCC) and inhibit the proliferation of human lung cancer cell line PC-9 mainly by blocking the cell cycle at G0/G1 via down-regulating the expression of Cyclin D1, Cyclin E. | |
| BCN2391 | Jolkinolide B |
| 1. Jolkinolide B can induce neuroendocrine differentiation of human prostate LNCaP cancer cell line. 2. Jolkinolide B can induce apoptosis in MDA-MB-231 cells through inhibition of the PI3K/Akt signaling pathway. 3. Jolkinolide B has potent anti-inflammatory activities, the mechanism may be attributed to its suppression of NF-κB and activation. 4. Jolkinolide B exhibits significant antitumor activity, it is able to enhance apoptosis of human leukemic HL-60 and THP-1 cells, at least in part, through downregulation of JAK2/STAT3 and bcl-2, and upregulation of Bax and cytosolic cytochrome c. | |
| BCN2395 | Sclareol |
| Sclareol possesses anti-cancer, anti-osteoarthritic, immune-regulation and anti-inflammatory activities, it inhibits the MMPs, iNOS and COX-2 expression on mRNA and protein levels, while increases the TIMP-1 expression, and over-production of NO and PGE2 is also suppressed by Sclareol ameliorated cartilage degradation. Sclareol induces plant resistance to root-knot nematode partially through ethylene-dependent enhancement of lignin accumulation. | |
| BCN2405 | Magnoflorine chloride |
| Magnoflorine is usually used as an anxiolytic chemical with anti-oxidant, α-tyrosinase inhibitory and anti-inflammationary activities. | |
| BCN2409 | Lycorine |
| Lycorine is a toxic crystalline alkaloid found in various Amaryllidaceae species that weakly inhibits acetylcholinesterase (AChE) and ascorbic acid biosynthesis.Lycorine has antiviral, and anti-cancer effects, the mechanisms of Lycorine on the multiple myeloma cell line ARH-77 are associated with G1 phase cell cycle arrest, mitochondrial dysfunction, reactive oxygen species (ROS) generation, ATP depletion, and DNA damage. | |
