Products with Anti-diabetic complications bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN2609 | Vinpocetine |
| Vinpocetine is a selective inhibitor of voltage-sensitive sodium channel for the treatment of stroke, vascular dementia and Alzheimer's disease. Vinpocetine can attenuate neointimal formation in diabetic rats and inhibit HG-induced VSMCs proliferation, chemokinesis and apoptotic resistance by preventing ROS activation and affecting MAPK, PI3K/Akt, and NF-κB signaling.Vinpocetine has anti-inflammatory activity, can treat inflammation and pain induced by a gram-negative bacterial component by targeting NF-κB activation and NF-κB-related cytokine production in macrophages. | |
| BCN2640 | Cycloart-23-ene-3,25-diol |
| 1. Cycloart-23-ene-3,25-diol has anti-inflammatory activity . 2. Cycloart-23-ene-3,25-diol has protective activity against streptozotocin induced toxicity. 3. Cycloart-23-ene-3,25-diol treatment can decrease liver malondialdehyde but increase superoxidase dismutase and reduced glutathione. | |
| BCN3013 | Vicenin -2 |
| Vicenin -2 has hepatoprotective, anti-cancer, antioxidant and anti-inflammatory activities, and DTL co-administration is more effective than either of the single agents in androgen-independent prostate cancer. Vicenin -2 might be a useful lead for the development of multiple target-oriented therapeutic modalities for the treatment of diabetes and diabetes-associated complications. Vicenin -2 could act as a UV light barrier to protect the plants. | |
| BCN3260 | Chebulic acid |
| 1. Chebulic acid at both doses (25 and 50 mg/kg) improves biochemical alterations caused by renal ischemia in diabetic rats. 2. Chebulic acid has effects against the progression of AGE-induced endothelial cell dysfunction, may constitute a promising intervention agent against diabetic vascular complications. 3. Chebulic acid significantly reduced the tert-butyl hydroperoxide (t-BHP)-induced cell cytotoxicity, intracellular reactive oxygen species level, and the ratio of GSSH, oxidized form of glutathione (GSH) to the over total GSH (GSH + GSSG) (4.42%) as compared to that with t-BHP alone (8.33%). | |
| BCN3341 | alpha-Amyrin |
| 1. Alpha-Amyrin is an antineoplastic agent. 2. Alpha-Amyrin is trypsin and chymotrypsin inhibitor. 3. Alpha-Amyrin induces proliferation of human keratinocytes. 4. Alpha-Amyrin can as a hepatomodulatory potent to feasibility for a promising liver curative drug. | |
