Products with Anti-cocaine addiction bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN2599 | L-Stepholidine |
| L-Stepholidine, which has dual actions on dopamine D1 and D2 receptors, attenuates heroin self-administration and cue-induced reinstatement. It also elicits anti-dyskinesia effects. | |
| BCN2723 | (-)-Isocorypalmine |
| (-)-Isocorypalmine has significant antifungal activity. l-isocorypalmine acts as a D1 partial agonist and a D2 antagonist to produce its in vivo effects and may be a promising agent for treatment of cocaine addiction. | |
| BCN4378 | Ibogaine |
| 1. Ibogaine has the propensity to prolong the QT interval of the electrocardiogram in humans, may generate life-threatening cardiac arrhythmias . 2. Ibogaine has promising anti-addictive property in animals. | |
| BCN6310 | Tetrahydropalmatine |
| Tetrahydropalmatine, a plant alkaloid used as an ingredient in dietary supplement products, is a potent and selective D1 receptor antagonist. Tetrahydropalmatine shows a promyogenic effect by upregulation of p38MAPK, Akt resulting in enhanced MyoD activation, it can effectively protect endothelial cells against γ-irradiation injury. Tetrahydropalmatine has a potential as a therapeutic candidate to prevent fibrosis and improve muscle regeneration and repair and applied to the prevention of endothelial cell dysfunctions associated with ionizing irradiation-induced lung injury. | |
