Others Products Targets
- Adenosine A2B Receptor (7)
- Adenosine A2A Receptor (11)
- Matrix Metalloprotease (16)
- LXR-like Receptor (6)
- Elastase (1)
- EGFR (28)
- Voltage-gated Sodium (NaV) Channel (30)
- Lipoxygenase (8)
- Leukotriene and Related Receptor (13)
- Others (6)
- Glucocorticoid Receptor (9)
- Cytokine Receptor (4)
- Cyclooxygenase (24)
- Vitamin D Receptor (10)
- Progesterone Receptor (4)
- Mineralocorticoid Receptor (7)
- Pregnane X Receptor (3)
- Constitutive Androstane Receptor (5)
- Aryl Hydrocarbon Receptor (8)
- 5-HT7 Receptor (11)
- 5-HT6 Receptor (14)
- 5-ht5 Receptor (2)
- 5-HT4 Receptor (17)
- GPR55 (8)
- CB2 Receptor (6)
- CB1 Receptor (17)
- Retinoic Acid-related Orphan Receptor (4)
- Rev-Erb Receptor (2)
- Estrogen and Related Receptor (33)
- Histamine H4 Receptor (12)
- Histamine H3 Receptor (22)
- Histamine H2 Receptor (10)
- Histamine H1 Receptor (17)
- Chemokine CXC Receptor (9)
- Chemokine CC Receptor (13)
- Adenosine A3 Receptor (8)
- Adenosine A1 Receptor (12)
- Calcitonin and Related Receptor (10)
- Androgen Receptor (11)
- Adrenergic α2 Receptor (33)
- Adrenergic α1 Receptor (22)
- Adrenergic β3 Receptor (12)
- Adrenergic β2 Receptor (6)
- Adrenergic β1 Receptor (7)
- Protease-Activated Receptor (23)
- Retinoid X Receptor (13)
- Retinoic Acid Receptor (22)
- Prostanoid Receptor (24)
- Sphingosine-1-Phosphate Receptor (13)
- Platelet-Activating Factor (PAF) Receptor (5)
- Phosphodiesterase (34)
Products for Others - Page 60
- Cat.No. Product Name Information/Activity
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BCC5075
A-803467
A 803467 is a selective Nav1.8 sodium channel blocker with an IC50 of 8 nM; over 100-fold more selective vs. human Nav1.2, 1.3, 1.5 and 1.7.
-
BCC7898
A 887826
A-887826 is a potent, selective, oral bioavailable and voltage-dependent Na(v)1.8 sodium channel blocker with an IC50 of 11 nM . A-887826 attenuates neuropathic tactile allodynia in vivo.
-
BCC5067
Ambroxol HCl
Na<sup>+</sup> channel blocker,AmbroxolHCl is a potent inhibitor of the neuronal Na+ channels, inhibits TTX-resistant Na+ currents with IC50 of 35.2 μM and 22.5 μM for tonic and phasic block, inhibits TTX-sensitive Na+ currents with IC50 of 100 μM. Phase 3.
-
BCC6294
APETx2
713544-47-9
-
BCC4378
Carbamazepine
Carbamazepine, a sodium channel blocker, is an anticonvulsant drug.
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BCC7439
Co 102862
181144-66-1
-
BCC1578
Flecainide acetate
Flecainide acetate (R-818) is a class 1C antiarrhythmic drug especially used for the management of supraventricular arrhythmia; works by blocking the Nav1.5 sodium channel in the heart, causing prolongation of the cardiac action potential.
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BCC4398
Flunarizine 2HCl
Flunarizine is a selective calcium entry blocker.
-
BCC6270
Huwentoxin IV
526224-73-7
-
BCC6358
ICA 121431
ICA-121431 is a nanomolar potent and broad-spectrum voltage-gated sodium channel (Nav) blocker, shows equipotent selectivity for human Nav1.1 and Nav1.3 subtypes with IC50 values of 13 nM and 23 nM, respectively. ICA-121431 shows less potent inhibition of Nav1.2 (IC50=240 nM) and 1,000 fold selectivity against Nav1.4, Nav1.6, and the TTX-resistant human Nav1.5 and Nav1.8 channels (IC50s >10 µM).
