Respiratory System Research
The respiratory system consists of the lungs, airways, diaphragm, trachea (windpipe) and pharynx (throat) and its primary function is the exchange of oxygen and carbon dioxide- breathing in and out. Between 6 and 10 liters of air are brought in and out of the lungs and 0.3 liters of oxygen are transferred from the alveoli to the blood per minute.
Respiratory System Research Products Areas
Products for Respiratory System Research - Page 55
- Cat.No. Product Name Information/Activity
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BCN2185
Retinoic acid
Retinoic acid is a metabolite of vitamin A that plays important roles in cell growth, differentiation, and organogenesis. Retinoic acid is a natural agonist of RAR nuclear receptors, with IC50s of 14 nM for RARα/β/γ. Retinoic acid bind to PPARβ/δ with Kd of 17 nM.
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BCC2540
Tazarotene
Tazarotene (AGN 190168) is a selective retinoic acid receptor (RAR) agonist for the treatment of plaque psoriasis and acne vulgaris.
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BCC4874
TTNPB (Arotinoid Acid)
TTNPB is a highly potent RAR agonist. Competitive binding assays using human RARs yield IC50s of α=5.1 nM, β= 4.5 nM, and γ=9.3 nM, respectively.
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BCC7740
BMS 195614
253310-42-8
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BCC7697
BMS 493
BMS493 is an inverse pan-retinoic acid receptor (RAR) agonist. BMS493 increases nuclear corepressor interaction with RARs. BMS493 also could prevent retinoic acid-induced differentiation.
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BCC7778
CD 2665
CD2665 is a selective RAR-beta/gamma antagonist, with Ki values of 110 nM, 306 nM for RARγ and RARβ, respectively.
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BCC7783
ER 50891
187400-85-7
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BCC7782
MM 11253
345952-44-5
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BCC7679
BMS 453
166977-43-1
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BCC6097
EC 23
EC23 (AGN 190205) is a stable synthetic retinoid analogue and induces neuronal differentiation.
