GABAA Receptor
GABAA receptors are members of the Cys-loop family of ligand-gated ion channels and, along with GABAB receptors, are responsible for mediating the inhibitory effects of GABA. They are pentameric proteins, consisting of five subunits belonging to different families.
Products for GABAA Receptor - Page 3
- Cat.No. Product Name Information/Activity
-
BCC7266
SCS
3232-36-8
-
BCC6997
SR 95531 hydrobromide
Gabazine is a selective and competitive antagonist of GABAA receptor, with an IC50 of ~0.2 μM for GABA receptor.
-
BCC7510
TB 21007
207306-50-1
-
BCC7471
U 93631
U93631 is a GABAA receptor ligand of novel chemical structure with IC50 of 100 nM,and has been shown to induce a rapid, time-dependent decay of GABA-induced whole-cell Cl-currents in recombinant GABAA receptors.
-
BCC5521
Emapunil
Emapunil(AC-5216;XBD-173) is a translocator protein [TSPO (18 kDa)] ligand.
-
BCC7711
Bretazenil
84379-13-5
-
BCC6635
β-CCB
84454-35-3
-
BCC7162
CL 218872
66548-69-4
-
BCC6671
Dihydroergotoxine mesylate
Dihydroergotoxine mesylate is a complex of closely related alkaloid salts; Binds with high affinity to the GABAA receptor Cl- channel, producing an allosteric interaction with the benzodiazepine site.
-
BCC7560
DMCM hydrochloride
DMCM hydrochloride is a nonselective full inverse agonist of benzodiazepine. DMCM shows bnding afinity at human recombinant GABAA αxβ3γ2 receptor subtypes with Kis of 10 nM, 13 nM, 7.5 nM, 2.2 nM for α1, α2, α3, and α5 receptors, respectively.
