Pain and Inflammation Research

Although separate conditions, pain and inflammation are nearly always associated with each other. Pain is defined by the International Association for the Study of Pain (IASP) as 'an unpleasant sensory and emotional experience associated with actual or potential tissue damage, or described in terms of such damage'. Inflammation is the tissue's immunologic response to injury, characterized by mobilization of white blood cells and antibodies, swelling, and fluid accumulation.

Pain and Inflammation Research Products Areas

Products for Pain and Inflammation Research - Page 65

Cat.No. Product Name Information/Activity
BCC6624 NBQX NBQX is a highly selective and competitive AMPA receptor antagonist.
BCC6907 NBQX disodium salt 479347-86-9
BCC7478 Philanthotoxin 74 Philanthotoxin 74 dihydrochloride (PhTx 74) is an AMPAR antagonist; inhibits GluR3 and GluR1 with IC50s of 263 and 296 nM, respectively.
BCC6866 SYM 2206 SYM 2206 is a novel, potent, non-competitive AMPA receptor antagonist.
BCC6378 Talampanel(LY300164) Talampanel is a potent and selective AMPA-receptor antagonist, is a potential new antiepileptic drug (AED).
BCC7171 UBP 282 544697-47-4
BCC7455 YM 90K hydrochloride 154164-30-4
BCC7339 ZK 200775 Fanapanel (ZK200775) is a highly selective AMPA/kainate antagonist with little activity against NMDA; have Ki values of 3.2 nM, 100 nM, and 8.5 μM against quisqualate, kainate, and NMDA, respectively.
BCC6151 CMPDA CMPDA is a positive allosteric modulator of AMPA receptors with EC50s of 45.4 ± 4.2 nM/63.4 ± 5.6 nM for GluA2i/GluA2o receptor.
BCC7532 CX 546 CX546 is a selective positive AMPAR modulator; the prototypical ampakine agent.