Pain and Inflammation Research

Although separate conditions, pain and inflammation are nearly always associated with each other. Pain is defined by the International Association for the Study of Pain (IASP) as 'an unpleasant sensory and emotional experience associated with actual or potential tissue damage, or described in terms of such damage'. Inflammation is the tissue's immunologic response to injury, characterized by mobilization of white blood cells and antibodies, swelling, and fluid accumulation.

Pain and Inflammation Research Products Areas

Products for Pain and Inflammation Research - Page 4

  1. Cat.No. Product Name Information/Activity
  2. BCC5948 SC 58125 162054-19-5 SC 58125 chemical structure
  3. BCC7809 SC 236 170569-86-5 SC 236 chemical structure
  4. BCC4861 Sulindac Sulindac (MK-231) is a non-steroidal antiinflammatory agent, acts as a COX-2 inhibitor, and inhibits overexpression of COX-2. Sulindac chemical structure
  5. BCC7391 Talniflumate 66898-62-2 Talniflumate chemical structure
  6. BCC7419 Tenidap Tenidap, a non-steroidal anti-inflammatory drug, is a selective COX-1 inhibitor, with IC50 values of 0.03 µM and 1.2 µM for COX-1 and COX-2, respectively. Tenidap has anti-inflammatory and antirheumatic properties. Tenidap is also a specific SLC26A3 inhibitor. Tenidap chemical structure
  7. BCC4441 Valdecoxib Valdecoxib is a highly potent and selective inhibitor of COX-2, with IC50s of 5 nM and 140 μM for COX-2 and COX-1, respeceively. Valdecoxib can be used in the research of arthritis and pain. Valdecoxib chemical structure
  8. BCC5812 AF 12198 Potent, selective human type I IL-1 receptor antagonist AF 12198 chemical structure
  9. BCC7149 YM 90709 YM-90709 is a novel antagonist which inhibits the binding of interleukin-5 to interleukin-5 receptor. YM 90709 chemical structure
  10. BCC5895 Lyn peptide inhibitor 222018-18-0 Lyn peptide inhibitor chemical structure
  11. BCC5813 Ro 26-4550 trifluoroacetate 1217448-66-2 Ro 26-4550 trifluoroacetate chemical structure

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