Pain and Inflammation Research

Although separate conditions, pain and inflammation are nearly always associated with each other. Pain is defined by the International Association for the Study of Pain (IASP) as 'an unpleasant sensory and emotional experience associated with actual or potential tissue damage, or described in terms of such damage'. Inflammation is the tissue's immunologic response to injury, characterized by mobilization of white blood cells and antibodies, swelling, and fluid accumulation.

Pain and Inflammation Research Products Areas

Products for Pain and Inflammation Research - Page 13

  1. Cat.No. Product Name Information/Activity
  2. BCC7175 Ro 106-9920 62645-28-7 Ro 106-9920 chemical structure
  3. BCC4554 SC-514 SC-514 is a selective IKK-2 inhibitor (IC50=11.2 μM), which does not inhibit other IKK isoforms or other serine-threonine and tyrosine kinases. SC-514 chemical structure
  4. BCC2545 Sulfasalazine Sulfasalazine is a drug for the treatment of rheumatoid arthritis and ulcerative colitis. Sulfasalazine is reported to suppress NF-κB activity. Sulfasalazine chemical structure
  5. BCN5763 Tanshinone IIA Tanshinone IIA (Tan IIA) is one of the main fat-soluble compositions in the root of red-rooted salvia. Tanshinone IIA may suppress angiogenesis by targeting the protein kinase domains of VEGF/VEGFR2. Tanshinone IIA chemical structure
  6. BCC2473 TPCA-1 TPCA-1 is a potent and selective inhibitor of IKK-2 with IC50 of 17.9 nM. TPCA-1 is an effective inhibitor of STAT3 phosphorylation, DNA binding, and transactivation. TPCA-1 chemical structure
  7. BCC7495 Withaferin A Withaferin A is a steroidal lactone isolated from Withania somnifera, inhibits NF-kB activation and targets vimentin, with potent antiinflammatory and anticancer activities. Withaferin A chemical structure
  8. BCN5524 Betulinic acid Betulinic acid is a natural pentacyclic triterpenoid, acts as a eukaryotic topoisomerase I inhibitor, with an IC50 of 5 μM, and possesses anti-HIV, anti-malarial, anti-inflammatory and anti-tumor properties. Betulinic acid acts as a new activator of NF-kB. Betulinic acid chemical structure
  9. BCC5160 ATP disodium salt ATP disodium salt is a phosphate-group donor for substrate activation in metabolic reactions and the coenzyme for a large number of kinases. ATP disodium salt chemical structure
  10. BCC7855 ATPγS tetralithium salt 93839-89-5 ATPγS tetralithium salt chemical structure
  11. BCC7643 BzATP triethylammonium salt 112898-15-4 BzATP triethylammonium salt chemical structure

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