Kainate Receptor
Kainate receptors are members of the ionotropic class of glutamate receptors, which also includes NMDA and AMPA receptors. Kainate receptors have been identified both pre- and post-synaptically. They contribute to excitatory postsynaptic currents in many regions of the CNS.
Products for Kainate Receptor - Page 2
- Cat.No. Product Name Information/Activity
-
BCC7407
GYKI 53655 hydrochloride
GYKI53655 hydrochloride is an α-amino-3-hydroxy-5-methylisoxazole-4-propionic acid (AMPA) antagonist.
-
BCC7275
NS 3763
70553-45-6
-
BCC6378
Talampanel(LY300164)
Talampanel is a potent and selective AMPA-receptor antagonist, is a potential new antiepileptic drug (AED).
-
BCC2314
Topiramate
Topiramate (McN 4853) is a broad-spectrum antiepileptic agent. Topiramate is a GluR5 receptor antagonist. Topiramate produces its antiepileptic effects through enhancement of GABAergic activity, inhibition of kainate/AMPA receptors, inhibition of voltage-sensitive sodium and calcium channels, increases in potassium conductance, and inhibition of carbonic anhydrase.
-
BCC7171
UBP 282
544697-47-4
-
BCC7255
UBP 296
745055-86-1
-
BCC7172
UBP 301
569371-10-4
-
BCC7256
UBP 302
UBP 302 is a potent and selective GLUK5-subunit containing kainate receptor antagonist (apparent Kd=402 nM), and displays very little affinity on GluK2 (GluR6) kainate receptors. Anxiolytic effects.
-
BCC6052
UBP 310
902464-46-4
-
BCC7339
ZK 200775
Fanapanel (ZK200775) is a highly selective AMPA/kainate antagonist with little activity against NMDA; have Ki values of 3.2 nM, 100 nM, and 8.5 μM against quisqualate, kainate, and NMDA, respectively.
