Neural Development

Neural development describes the growth and development of the nervous system starting from embryogenesis and continuing throughout life.

Neural Development Products Targets

Cat.No. Product Name Information/Activity
BCC6574 Guvacine hydrochloride Guvacine hydrochloride is an alkaloid from the nut of Areca catechu, acts as an inhibitor of GABA transporter, and dispalys modest selectivity for cloned GABA transporters with IC50s of 14 μM (human GAT-1), 39 μM (rat GAT-1), 58 μM (rat GAT-2), 119 μM (human GAT-3), 378 μM (rat GAT-3), and 1870 μM (human BGT-3).
BCC6576 (±)-Nipecotic acid 60252-41-7
BCC7472 NNC 05-2090 hydrochloride 184845-18-9
BCC7176 NNC 711 145645-62-1
BCC6930 SKF 89976A hydrochloride SKF89976A hydrochloride is a selective GABA transporter (GAT-1) inhibitor with IC50s of 0.28 μM, 137.34 μM and 202.8 μM for GAT-1, GAT-2 and GAT-3 in CHO cells, respectively.
BCC7117 (S)-SNAP 5114 (S)-SNAP5114 is a selective GABA transport inhibitor, with IC50 values of 5 μM and 21 μM for hGAT-3 and rGAT-2, respectively. (S)-SNAP5114 is an anticonvulsant drug.
BCC5217 Tiagabine hydrochloride Tiagabine hydrochloride is a potent and selective GABA reuptake inhibitor, used as an anticonvulsant agent, with IC50s of 67, 446 and 182 nM for [3H]GABA uptake in Synaptosomes, Neurons and Glia, respectively.
BCC6587 cis-ACBD 73550-55-7
BCC6608 L-CCG-lll 117857-95-1
BCC6816 Chicago Sky Blue 6B 2610-05-1