Multiple Sclerosis

Multiple sclerosis (MS) is a chronic autoimmune, inflammatory disease of the central nervous system (CNS), which causes damage to myelin and axons, resulting in neurological symptoms such as partial loss of sight, paresthesias and ataxia.

Multiple Sclerosis Products Targets

Products for Multiple Sclerosis - Page 41

Cat.No. Product Name Information/Activity
BCC1573 FH535 FH535 is an inhibitor of Wnt/β-catenin and PPAR, with anti-tumor activities.
BCC3632 ICG 001 ICG-001 antagonizes Wnt/β-catenin/TCF-mediated transcription and specifically binds to CREB-binding protein (CBP) with IC50 of 3 μM, but is not the related transcriptional coactivator p300.
BCC5401 iCRT 14 iCRT 14 is a novel potent inhibitor of β-catenin-responsive transcription (CRT), with IC50 of 40.3 nM against Wnt responsive STF16 luciferase.
BCC5602 IWP 4 IWP-4 is a small molecule Wnt inhibitor with an IC50 of 25 nM.
BCC5102 IWR-1-endo IWR-1 is a tankyrase inhibitor which inhibits Wnt/β-catenin signaling pathway.
BCC7823 exo-IWR 1 1127442-87-8
BCC6251 JW 67 442644-28-2
BCC7704 PNU 74654 PNU-74654 is an inhibitor of Wnt/β-catenin pathway with an IC50 of 129.8 μM in NCI-H295 cell.
BCC3968 TAK-715 TAK-715 is a p38 MAPK inhibitor for p38α with IC50 of 7.1 nM, 28-fold more selective for p38α over p38β, no inhibition to p38γ/δ, JNK1, ERK1, IKKβ, MEKK1 or TAK1.
BCC5614 CKI 7 dihydrochloride 1177141-67-1