Neuroscience Research

Neuroscience is the study of the nervous system - one of the major mammalian systems responsible for sustaining life. The central nervous system (CNS) and peripheral nervous system (PNS) work in concert to coordinate basic functions such as moving and breathing, as well as 'higher order' functions including thought, speech and emotion.

Neuroscience Research Products Areas

Products for Neuroscience Research - Page 37

Cat.No. Product Name Information/Activity
BCC7105 DCPIB DCPIB is a selective, reversible and potent inhibitor of volume-regulated anion channels (VRAC), voltage-dependently activates potassium channels TREK1 and TRAAK, inhibits TRESK, TASK1 and TASK3 (IC50s, 0.14, 0.95, 50.72 μM, respectively). DCPIB is also a selective blocker of swelling-induced chloride current (ICl,swell), with an IC50 of 4.1 μM in CPAE cells.
BCC7942 DIDS Chloride channel blocker; TRPV1 modulator; RAD51 recombinase inhibitor
BCC6326 GaTx2 194665-85-5
BCC4784 Glyburide Glibenclamide is a selective inhibitor of ATP-sensitive K+ channel.
BCC4104 GlyH-101 GlyH-101 is a cell-permeable glycinyl hydrazone compound that blocks CFTR with Ki of 1.4 uM.
BCC6711 NPPB NPPB is a blocker of the outwardly rectifying chloride channel (ORCC).
BCC5248 PPQ-102 PPQ-102 is a potent CFTR inhibitor which can completely inhibited CFTR chloride current with IC50 of ~90 nM.
BCC6220 T16Ainh - A01 T16Ainh-A01, an aminophenylthiazole, is a potent transmembrane protein 16A (TMEM16A) inhibitor, inhibiting TMEM16A-mediated chloride currents with an IC50 value of ~1 µM. TMEM16A (ANO1) functions as a calcium-activated chloride channel (CaCC).
BCC7578 KM 11060 KM11060 is a novel corrector of the F508del-CFTR trafficking defect.
BCC7820 PG 01 PG01 is a potent CFTR Cl- channel potentiator. PG01 can correct gating defects of CFTR mutants, is effective on b>E193K