Cardiovascular System Research

The cardiovascular, or circulatory, system is a closed elastic circuit consisting of the heart, blood vessels (arteries, capillaries and veins) and the blood. The primary function is to pump oxygenated blood to the tissues throughout the body and reabsorb waste carbon dioxide for its removal. This function is performed by the use of pulmonary and systemic circulation.

Cardiovascular System Research Products Areas

Products for Cardiovascular System Research - Page 37

  1. Cat.No. Product Name Information/Activity
  2. BCC4634 Benzbromarone Benzbromarone is a highly effective and well tolerated non-competitive inhibitor of xanthine oxidase, used as an uricosuric agent, used in the treatment of gout. Benzbromarone chemical structure
  3. BCC6314 CaCCinh-A01 CaCCinh-A01 is an inhibitor of both TMEM16A and calcium-activated chloride channel (CaCC) with IC50s of 2.1 and 10 μM, respectively. CaCCinh-A01 chemical structure
  4. BCC4419 CFTRinh-172 CFTR(inh)-172 is a potent and selective blocker of the CFTR chloride channel; reversibly inhibits CFTR short-circuit current in less than 2 minutes with a Ki of 300 nM. CFTRinh-172 chemical structure
  5. BCC7055 Chromanol 293B 163163-23-3 Chromanol 293B chemical structure
  6. BCC7105 DCPIB DCPIB is a selective, reversible and potent inhibitor of volume-regulated anion channels (VRAC), voltage-dependently activates potassium channels TREK1 and TRAAK, inhibits TRESK, TASK1 and TASK3 (IC50s, 0.14, 0.95, 50.72 μM, respectively). DCPIB is also a selective blocker of swelling-induced chloride current (ICl,swell), with an IC50 of 4.1 μM in CPAE cells. DCPIB chemical structure
  7. BCC7942 DIDS Chloride channel blocker; TRPV1 modulator; RAD51 recombinase inhibitor DIDS chemical structure
  8. BCC6326 GaTx2 194665-85-5 GaTx2 chemical structure
  9. BCC4784 Glyburide Glibenclamide is a selective inhibitor of ATP-sensitive K+ channel. Glyburide chemical structure
  10. BCC4104 GlyH-101 GlyH-101 is a cell-permeable glycinyl hydrazone compound that blocks CFTR with Ki of 1.4 uM. GlyH-101 chemical structure
  11. BCC6711 NPPB NPPB is a blocker of the outwardly rectifying chloride channel (ORCC). NPPB chemical structure

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