Thrombosis and Hemostasis Research

Thrombosis is a crucial hemostatic process for maintaining blood volume (hemostasis) following injury, yet aberrant thrombosis can trigger pathological conditions including myocardial infarction and stroke. Therefore the initiation of thrombosis is tightly controlled under physiological conditions.

Products for Thrombosis and Hemostasis Research - Page 7

Cat.No. Product Name Information/Activity
BCC6692 MMPX 78033-08-6
BCC6645 MY-5445 MY-5445 is a specific phosphodiesterase type 5 (PDE5) inhibitor. MY-5445 selectively inhibits cGMP PDE with a Ki of 1.3 μM.
BCC6215 Piclamilast 144035-83-6
BCC6638 Ro 20-1724 29925-17-5
BCC2282 Rolipram Rolipram is a selective phosphodiesterases PDE4 inhibitor with IC50s of 3 nM, 130 nM and 240 nM for PDE4A, PDE4B, and PDE4D, respectively.
BCC5429 (R)-(-)-Rolipram (R)-(-)-Rolipram is the R-enantiomer of Rolipram. Rolipram is a selective inhibitor of phosphodiesterases PDE4 with IC50 of 3 nM, 130 nM and 240 nM for PDE4A, PDE4B, and PDE4D, respectively.
BCC2303 S- (+)-Rolipram (S)-(+)-Rolipram is a PDE4-inhibitor and an anti-inflammatory agent, less potent than its R enantiomer.
BCC7645 RS 25344 hydrochloride 152815-28-6
BCC6954 Siguazodan Siguazodan (SKF 94836) is a potent, selective and orally active phosphodiesterase III (PDE-III) inhibitor with an IC50 of 117 nM. Siguazodan increases cAMP accumulation in intact platelets with an EC50 of 18.88 μM. Siguazodan also inhibits phenylephrine-induced 5-HT release with an IC50 value of 4.2 μM.
BCC2276 Sildenafil Citrate Sildenafil citrate is a potent phosphodiesterase type 5 (PDE5) inhibitor with IC50 of 5.22 nM.

Thrombosis and Hemostasis Research

Thrombosis and Hemostasis Research Products Targets

Products for Thrombosis and Hemostasis Research - Page 7