Thrombosis and Hemostasis Research

Thrombosis is a crucial hemostatic process for maintaining blood volume (hemostasis) following injury, yet aberrant thrombosis can trigger pathological conditions including myocardial infarction and stroke. Therefore the initiation of thrombosis is tightly controlled under physiological conditions.

Products for Thrombosis and Hemostasis Research - Page 30

Cat.No. Product Name Information/Activity
BCC5994 [Lys5,MeLeu9,Nle10]-NKA(4-10) 137565-28-7
BCC7001 GR 159897 GR 159897 is a highly potent, selective, competitive, brain-penetrated non-peptide neurokinin 2 (NK2) receptor antagonist. GR 159897 has little or no affinity for NK1 and NK3 receptors. GR 159897 inhibits binding of [3H]GR100679 to human NK2 (hNK2)-CHO cells and rat colon membranes with pKis of 9.51 and 10, respectively. Antagonizes bronchoconstriction. Anxiolytic-like and anti-tumor effects.
BCC5799 GR 94800 141636-65-9
BCC5729 MDL 29,913 135721-56-1
BCC7133 MEN 10376 Men 10376 is a selective tachykinin NK-2 receptor antagonist, with a Ki of 4.4 μM for rat small intestine NK-2 receptor.
BCC6921 Senktide Senktide is a tachykinin NK3 receptor agonist.
BCC7037 SB 218795 174635-53-1
BCC1926 SB-222200 SB 222200 is a selective, reversible and competitive antagonist of human NK-3 receptor(Ki=4.4 nM) that effectively crosses the blood-brain barrier.
BCC1981 Talnetant Talnetant (SB 223412) is a potent and selective NK3 receptor antagonist (ki=1.4 nM, hNK-3-CHO); 100-fold selective for the hNK-3 versus hNK-2 receptor, with no affinity for the hNK-1 at concentrations up to 100 uM.
BCC7635 SSR 146977 hydrochloride 264618-38-4

Thrombosis and Hemostasis Research

Thrombosis and Hemostasis Research Products Targets

Products for Thrombosis and Hemostasis Research - Page 30