Cardiovascular Research

The cardiovascular, or circulatory, system is a closed elastic circuit consisting of the heart, blood vessels (arteries, capillaries and veins) and the blood. The primary function is to pump oxygenated blood to the tissues throughout the body and reabsorb waste carbon dioxide for its removal. This function is performed by the use of pulmonary and systemic circulation.

Cardiovascular Research Products Areas

Products for Cardiovascular Research - Page 88

Cat.No. Product Name Information/Activity
BCC6963 BQ-123 BQ-123 is a selective endothelin A receptors (ETAR) antagonist with an IC50 value of 7.3 nM and a Ki vaule of 25 nM.
BCC7523 CI 1020 162256-50-0
BCC5733 FR 139317 142375-60-8
BCC4860 Sulfisoxazole Sulfisoxazole, an endothelin receptor antagonist, is a sulfonamide antibacterial with an oxazole substituent.
BCC5728 BQ-3020 Selective ET<sub>B</sub> agonist
BCC5731 [Ala1,3,11,15]-Endothelin 121204-87-3
BCC5721 Sarafotoxin S6c 121695-87-2
BCC5151 BQ-788 sodium salt BQ-788 (sodium salt) is a potent and selective ETB receptor antagonist, inhibiting ET-1 binding to ETB receptors with an IC50 of 1.2 nM in human Girrardi heart cells.
BCC7192 IRL-2500 IRL 2500 is a potent Endothelin receptor antagonist. IRL 2500 shows IC50 values of 1.3 and 94 nM for ETB and ETA receptors, respectively. IRL 2500 inhibits ETB receptor-mediated blood pressure increase and renal vascular resistance in rats in vivo.