Cardiovascular Research

The cardiovascular, or circulatory, system is a closed elastic circuit consisting of the heart, blood vessels (arteries, capillaries and veins) and the blood. The primary function is to pump oxygenated blood to the tissues throughout the body and reabsorb waste carbon dioxide for its removal. This function is performed by the use of pulmonary and systemic circulation.

Cardiovascular Research Products Areas

Products for Cardiovascular Research - Page 103

Cat.No. Product Name Information/Activity
BCC1808 NPS-2143 hydrochloride NPS-2143 hydrochloride (SB-262470A hydrochloride), an orally active calcilytic agent, is a selective and potent calcium ion-sensing receptor (CaSR) antagonist. NPS-2143 hydrochloride (SB-262470A hydrochloride) blocks increases in cytoplasmic Ca2+ concentrations (IC50=43 nM) elicited by activating the Ca2+ receptor in HEK 293 cells expressing the human Ca2+ receptor.
BCC7931 Calhex 231 hydrochloride Negative allosteric modulator of the calcium-sensing receptor
BCC7781 R 568 hydrochloride Tecalcet Hydrochloride (R 568 Hydrochloride), an orally active calcimimetic compound, allosterically and positively modulates the calcium-sensing receptor (CaSR). Tecalcet Hydrochloride (R 568 Hydrochloride) increases the sensitivity to activation by extracellular Ca2+.
BCC5801 GR 73632 GR-73632 is a novel tachykinin neurokinin 1 (NK-1) receptor agonist. GR-73632 acts directly on the peripheral terminals of primary sensory neurons through NK1 receptor which convey itch signals.
BCC5923 Hemokinin 1 (human) 491851-53-7
BCC5774 Hemokinin 1 (mouse) Hemokinin 1 (mouse) is a selective agonist of neurokinin-1 receptor, with Ki of 0.175 nM and 560 nM for human NK1 receptor and human NK2 receptor, respectively.
BCC6960 [Sar9,Met(O2)11]-Substance P [Sar9,Met(O2)11]-Substance P is a tachykinin NK1 receptor selective agonist.
BCC7509 CP 96345 132746-60-2
BCC6016 CP 99994 dihydrochloride 145148-39-6
BCC5907 FK 888 138449-07-7