Taxuspine W

CAS# 181309-92-2

Taxuspine W

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Taxuspine W:5mg Please Inquire In Stock
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Taxuspine W:20mg Please Inquire In Stock
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Quality Control of Taxuspine W

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Chemical structure

Taxuspine W

3D structure

Chemical Properties of Taxuspine W

Cas No. 181309-92-2 SDF Download SDF
PubChem ID 5321766 Appearance Powder
Formula C26H36O9 M.Wt 492.57
Type of Compound Diterpenoids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name [(1E,3S,4R,6S,9R,11S,12S,14S)-3,12-diacetyloxy-9,14-dihydroxy-7,11,16,16-tetramethyl-10-oxo-6-tricyclo[9.3.1.14,8]hexadeca-1,7-dienyl] acetate
SMILES CC1=C2C(C(=O)C3(CC(=CC(C(C2(C)C)CC1OC(=O)C)OC(=O)C)C(CC3OC(=O)C)O)C)O
Standard InChIKey ZUIZFJGNEDXNJD-MKSBNKCPSA-N
Standard InChI InChI=1S/C26H36O9/c1-12-19(33-13(2)27)9-17-20(34-14(3)28)8-16-11-26(7,21(10-18(16)30)35-15(4)29)24(32)23(31)22(12)25(17,5)6/h8,17-21,23,30-31H,9-11H2,1-7H3/b16-8+/t17-,18-,19-,20-,21-,23+,26-/m0/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Taxuspine W

The stems of the Japanese yew Taxus cuspidata Sieb. et Zucc.

Biological Activity of Taxuspine W

DescriptionTaxuspine W is a natural product from the Japanese yew Taxus cuspidata Sieb. et Zucc.

Protocol of Taxuspine W

Structure Identification
Tetrahedron, 1996, 52(41):13145-50.

Taxuspines U, V, and W, new taxane and related diterpenoids from the Japanese yew Taxus cuspidata[Reference: WebLink]


METHODS AND RESULTS:
Three new taxane and related diterpenoids, taxuspine U, taxuspine V, and Taxuspine W (1 ≈ 3), have been isolated from stems of the Japanese yew Taxus cuspidata Sieb, et Zucc. and the structures elucidated on the basis of spectroscopic data. Taxuspine U (1) is a very rare bicyclic taxane related diterpenoid from yew trees of genus Taxus, while Taxuspine W (3) is a rare taxoid having a 2(3→20)-abeotaxane skeleton.
CONCLUSIONS:
Three new taxane and related diterpenoids, taxuspine U (1), taxuspine V, and Taxuspine W have been isolated from stems of the Japanese yew Taxus cuspidata Sieb. et Zucc.

Taxuspine W Dilution Calculator

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Taxuspine W Molarity Calculator

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Preparing Stock Solutions of Taxuspine W

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.0302 mL 10.1508 mL 20.3017 mL 40.6034 mL 50.7542 mL
5 mM 0.406 mL 2.0302 mL 4.0603 mL 8.1207 mL 10.1508 mL
10 mM 0.203 mL 1.0151 mL 2.0302 mL 4.0603 mL 5.0754 mL
50 mM 0.0406 mL 0.203 mL 0.406 mL 0.8121 mL 1.0151 mL
100 mM 0.0203 mL 0.1015 mL 0.203 mL 0.406 mL 0.5075 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Taxuspine W

Laser Desorption/Ionisation Mass Spectrometry Imaging of European Yew (Taxus baccata) on Gold Nanoparticle-enhanced Target.[Pubmed:28523824]

Phytochem Anal. 2017 Sep;28(5):448-453.

INTRODUCTION: European yew (Taxus baccata) is a plant known to man for centuries as it produces many interesting and important metabolites. These chemical compounds were repeatedly analysed by various analytical techniques, but none of the methods used so far allowed the localisation of the chemical compounds within the tissue and also correlation between plant morphology and its biochemistry. OBJECTIVE: Visualisation of the spatial distribution of yew metabolites with nanoparticle-based mass spectrometry imaging. METHODOLOGY: Compounds occurring on cross-section of a one-year yew sprig has been transferred to gold nanoparticle-enhanced target (AuNPET) by imprinting. The imprint was then subjected to mass spectrometry imaging analysis. RESULTS: Nanoparticle-enhanced mass spectrometry imaging made it possible to study the distribution of selected compounds in the European yew tissue, including taxanes - terpene alkaloids characteristic for the Taxus genus. Results prove that aspartate, taxinine M, baccatin IV and taxine B are located mainly in the cortex. Taxuspine W was located in the vascular tissue. Maleate was found to be located mainly in the phloem tissue. In contrast, the proton adduct of chlorophyll b was found in the external layer of twigs. CONCLUSION: The results presented a high correlation between the location of compounds and the morphology of the plant, thus giving the opportunity to see the selected details of chemical structure of the analysed tissue for the first time. Copyright (c) 2017 John Wiley & Sons, Ltd.

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