Serrin A

CAS# 845959-98-0

Serrin A

Catalog No. BCN6985----Order now to get a substantial discount!

Product Name & Size Price Stock
Serrin A:5mg Please Inquire In Stock
Serrin A:10mg Please Inquire In Stock
Serrin A:20mg Please Inquire In Stock
Serrin A:50mg Please Inquire In Stock

Quality Control of Serrin A

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Chemical structure

Serrin A

3D structure

Chemical Properties of Serrin A

Cas No. 845959-98-0 SDF Download SDF
PubChem ID 11269305 Appearance Powder
Formula C22H30O6 M.Wt 390.47
Type of Compound Diterpenoids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name (1S,4S,8R,9R,12R,13S,16R)-9-ethoxy-11-hydroxy-7,7-dimethyl-17-methylidene-3,10-dioxapentacyclo[14.2.1.01,13.04,12.08,12]nonadecane-2,18-dione
SMILES CCOC1C2C(CCC3C2(C4CCC5CC4(C(=O)C5=C)C(=O)O3)C(O1)O)(C)C
Standard InChIKey BYOLCBRZEMRXHS-BGPRIOEDSA-N
Standard InChI InChI=1S/C22H30O6/c1-5-26-17-15-20(3,4)9-8-14-22(15,19(25)28-17)13-7-6-12-10-21(13,18(24)27-14)16(23)11(12)2/h12-15,17,19,25H,2,5-10H2,1,3-4H3/t12-,13-,14+,15-,17-,19?,21+,22+/m1/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Serrin A

The herbs of Rabdosia serra.

Biological Activity of Serrin A

Description1. Serrin A shows weak to moderate cytotoxic activities (IC50<10 uM) against two human cancer cell lines.

Serrin A Dilution Calculator

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Serrin A Molarity Calculator

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Preparing Stock Solutions of Serrin A

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.561 mL 12.8051 mL 25.6102 mL 51.2203 mL 64.0254 mL
5 mM 0.5122 mL 2.561 mL 5.122 mL 10.2441 mL 12.8051 mL
10 mM 0.2561 mL 1.2805 mL 2.561 mL 5.122 mL 6.4025 mL
50 mM 0.0512 mL 0.2561 mL 0.5122 mL 1.0244 mL 1.2805 mL
100 mM 0.0256 mL 0.1281 mL 0.2561 mL 0.5122 mL 0.6403 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Serrin A

ent-6,7-Secokaurane diterpenoids from Rabdosia serra and their cytotoxic activities.[Pubmed:26671519]

Phytochemistry. 2016 Feb;122:119-125.

Investigation of the hydrophobic extract of Rabdosia serra (Lamiaceae) led to the isolation of seven ent-6,7-secokaurane diterpenoids rabdosins E-K, along with twelve known ent-kaurane diterpenoids. Their structures were established by extensive spectroscopic analysis. The absolute configurations of rabdosins E, F, H and I were determined by single-crystal X-ray diffraction, with rabdosin E having a 3,20-epoxy group. These diterpenoids could be divided into two types according to their skeletons: rabdosins E-J are ent-6,20-epoxy-6,7-secokaur-1,7-olides, and rabdosin K is an ent-6,7-secokaur-7,20-olide. Cytotoxicity evaluation showed that serrin B, Serrin A, isodocarpin and lushanrubescensin J exhibited weak to moderate cytotoxic activities (IC50<10muM) against two human cancer cell lines.

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