Rabdoserrin A

CAS# 96685-01-7

Rabdoserrin A

Catalog No. BCN8041----Order now to get a substantial discount!

Product Name & Size Price Stock
Rabdoserrin A:5mg Please Inquire In Stock
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Rabdoserrin A:20mg Please Inquire In Stock
Rabdoserrin A:50mg Please Inquire In Stock

Quality Control of Rabdoserrin A

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Chemical structure

Rabdoserrin A

3D structure

Chemical Properties of Rabdoserrin A

Cas No. 96685-01-7 SDF Download SDF
PubChem ID 124223329 Appearance Powder
Formula C20H26O5 M.Wt 346.42
Type of Compound Diterpenoids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name (2S,5R,8R,10R,11S,14R,17S,18R,20R)-2,20-dihydroxy-5-methyl-13-methylidene-7,9-dioxahexacyclo[8.7.2.111,14.01,8.05,18.011,17]icosan-12-one
SMILES CC12CCC(C34C1CC(C56C3CCC(C5O)C(=C)C6=O)OC4OC2)O
Standard InChIKey MOBGVVQDJSDAER-ASWVVCDDSA-N
Standard InChI InChI=1S/C20H26O5/c1-9-10-3-4-11-19-12-7-14(20(11,15(9)22)16(10)23)25-17(19)24-8-18(12,2)6-5-13(19)21/h10-14,16-17,21,23H,1,3-8H2,2H3/t10-,11+,12-,13+,14-,16-,17-,18+,19?,20+/m1/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Rabdoserrin A

The herbs of Rabdosia serra

Biological Activity of Rabdoserrin A

In vitro

Antifungal activity and active ingredients of Rabdosia nervosa.[Reference: WebLink]

Acta Phytophylacica Sinica, 2010, 37(1):67-72.


METHODS AND RESULTS:
The antifungal activity of methanol extract and active ingredients of Rabdosia nervosa were studied by using mycelial growth, column chromatography and spectral analysis. The results showed that the methanol extract presents the highest inhibitory activity against Phytophthora melonis, Peronophthora litchi and the active ingredients mainly concentrated in the chloroform extract. Six active ingredients were isolated: lasiokaurin, Rabdoserrin A, oridonin, nodosin, epinodosinol and enmein. The inhibitory rates against Phytophthora melonis of six active ingredients in 20 μg/mL were 54.61%, 42.73%, 75.50%, 59.84%, 51.11%, 24.13% respectively and 49.52%, 19.45%, 76.81%, 10.29%, 2.63%, 7.09% against Peronophthora litchi respectively, oridonin had the most remarkable antifungal activity.
CONCLUSIONS:
Oridonin could induce the mycelium over branch that was observed with optical microscope and its mechanism deserves further study.

Rabdoserrin A Dilution Calculator

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Rabdoserrin A Molarity Calculator

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Preparing Stock Solutions of Rabdoserrin A

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.8867 mL 14.4333 mL 28.8667 mL 57.7334 mL 72.1667 mL
5 mM 0.5773 mL 2.8867 mL 5.7733 mL 11.5467 mL 14.4333 mL
10 mM 0.2887 mL 1.4433 mL 2.8867 mL 5.7733 mL 7.2167 mL
50 mM 0.0577 mL 0.2887 mL 0.5773 mL 1.1547 mL 1.4433 mL
100 mM 0.0289 mL 0.1443 mL 0.2887 mL 0.5773 mL 0.7217 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Rabdoserrin A

Antifungal activity and active ingredients of Rabdosia nervosa.

Acta Phytophylacica Sinica, 2010, 37(1):67-72.

The antifungal activity of methanol extract and active ingredients of Rabdosia nervosa were studied by using mycelial growth, column chromatography and spectral analysis. The results showed that the methanol extract presents the highest inhibitory activity against Phytophthora melonis, Peronophthora litchi and the active ingredients mainly concentrated in the chloroform extract. Six active ingredients were isolated: lasiokaurin, Rabdoserrin A, oridonin, nodosin, epinodosinol and enmein. The inhibitory rates against Phytophthora melonis of six active ingredients in 20 μg/mL were 54.61%, 42.73%, 75.50%, 59.84%, 51.11%, 24.13% respectively and 49.52%, 19.45%, 76.81%, 10.29%, 2.63%, 7.09% against Peronophthora litchi respectively, oridonin had the most remarkable antifungal activity. Oridonin could induce the mycelium over branch that was observed with optical microscope and its mechanism deserves further study.

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