Pseudolaric acid A-O-beta-D-glucopyranosideCAS# 98891-44-2 |
Quality Control & MSDS
Number of papers citing our products
Chemical structure
3D structure
| Cas No. | 98891-44-2 | SDF | Download SDF |
| PubChem ID | 44566375 | Appearance | White powder |
| Formula | C28H38O11 | M.Wt | 550.6 |
| Type of Compound | Diterpenoids | Storage | Desiccate at -20°C |
| Solubility | Soluble in chloroform, DMSO and ethan | ||
| SMILES | CC1=CCC23CCC(C2(CC1)OC(=O)C)C(OC3=O)(C)C=CC=C(C)C(=O)OC4C(C(C(C(O4)CO)O)O)O | ||
| Standard InChIKey | IVYWRYGMQNKDQB-VHJBJYHKSA-N | ||
| Standard InChI | InChI=1S/C28H38O11/c1-15-7-11-27-12-9-19(28(27,13-8-15)38-17(3)30)26(4,39-25(27)35)10-5-6-16(2)23(34)37-24-22(33)21(32)20(31)18(14-29)36-24/h5-7,10,18-22,24,29,31-33H,8-9,11-14H2,1-4H3/b10-5+,16-6+/t18-,19+,20-,21+,22-,24+,26-,27-,28+/m1/s1 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
||
| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
||
| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
| In vitro | Simultaneous determination of seven major diterpenoids in Pseudolarix kaempferi by high-performance liquid chromatography DAD method.[Pubmed: 17446030 ]J Pharm Biomed Anal. 2007 Jul 27;44(3):730-6.
|
| In vivo | Metabolic pathway and metabolites of total diterpene acid isolated from Pseudolarix kaempferi.[Pubmed: 25322560]Yao Xue Xue Bao. 2014 Aug;49(8):1169-74.The preliminary metabolic profile of total diterpene acid (TDA) isolated from Pseudolarix kaempferi was investigated by using in vivo and in vitro tests. |
Pseudolaric acid A-O-beta-D-glucopyranoside Dilution Calculator
Pseudolaric acid A-O-beta-D-glucopyranoside Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 1.8162 mL | 9.081 mL | 18.162 mL | 36.324 mL | 45.405 mL |
| 5 mM | 0.3632 mL | 1.8162 mL | 3.6324 mL | 7.2648 mL | 9.081 mL |
| 10 mM | 0.1816 mL | 0.9081 mL | 1.8162 mL | 3.6324 mL | 4.5405 mL |
| 50 mM | 0.0363 mL | 0.1816 mL | 0.3632 mL | 0.7265 mL | 0.9081 mL |
| 100 mM | 0.0182 mL | 0.0908 mL | 0.1816 mL | 0.3632 mL | 0.4541 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
Calcutta University
University of Minnesota
University of Maryland School of Medicine
University of Illinois at Chicago
The Ohio State University
University of Zurich
Harvard University
Colorado State University
Auburn University
Yale University
Worcester Polytechnic Institute
Washington State University
Stanford University
University of Leipzig
Universidade da Beira Interior
The Institute of Cancer Research
Heidelberg University
University of Amsterdam
University of Auckland
TsingHua University
The University of Michigan
Miami University
DRURY University
Jilin University
Fudan University
Wuhan University
Sun Yat-sen University
Universite de Paris
Deemed University
Auckland University
The University of Tokyo
Korea University
- Pseudolaric acid B-O-beta-D-glucopyranoside
Catalog No.:BCN1291
CAS No.:98891-41-9
- Danshenxinkun D
Catalog No.:BCN2472
CAS No.:98873-76-8
- FLAG tag Peptide
Catalog No.:BCC2562
CAS No.:98849-88-8
- (R)-(+)-Bay K 8644
Catalog No.:BCC7107
CAS No.:98791-67-4
- 3-(4-Hydroxy-3-methoxyphenyl)propyl tetracosanoate
Catalog No.:BCN1292
CAS No.:98770-70-8
- Reboxetine mesylate
Catalog No.:BCC4934
CAS No.:98769-84-7
- Isothymusin
Catalog No.:BCN4532
CAS No.:98755-25-0
- Latifoline N-oxide
Catalog No.:BCN1979
CAS No.:98752-06-8
- Paeonilactone A
Catalog No.:BCN3967
CAS No.:98751-79-2
- Paeonilactone B
Catalog No.:BCN3963
CAS No.:98751-78-1
- Paeonilactone C
Catalog No.:BCN3964
CAS No.:98751-77-0
- Ropivacaine HCl
Catalog No.:BCC4841
CAS No.:98717-15-8
- 3-Epiursolic acid
Catalog No.:BCN3173
CAS No.:989-30-0
- (-)-Epigallocatechin gallate
Catalog No.:BCN6326
CAS No.:989-51-5
- Limonol
Catalog No.:BCN4533
CAS No.:989-61-7
- Fmoc-His(Fmoc)-OH
Catalog No.:BCC3500
CAS No.:98929-98-7
- Fmoc-Arg(Mtr)-OH
Catalog No.:BCC3074
CAS No.:98930-01-9
- 3,5-DHBA
Catalog No.:BCC7951
CAS No.:99-10-5
- Ac-DL-Leu-OH
Catalog No.:BCC2977
CAS No.:99-15-0
- Prunasin
Catalog No.:BCN4535
CAS No.:99-18-3
- Trehalose
Catalog No.:BCC9182
CAS No.:99-20-7
- Methyl gallate
Catalog No.:BCN3823
CAS No.:99-24-1
- Chelidonic acid
Catalog No.:BCN6547
CAS No.:99-32-1
- 2-Methyl-5-Isopropenyl-2-Cyclohexenone
Catalog No.:BCC8279
CAS No.:99-49-0
[Metabolic pathway and metabolites of total diterpene acid isolated from Pseudolarix kaempferi].[Pubmed:25322560]
Yao Xue Xue Bao. 2014 Aug;49(8):1169-74.
The preliminary metabolic profile of total diterpene acid (TDA) isolated from Pseudolarix kaempferi was investigated by using in vivo and in vitro tests. Pseudolaric acid C2 (PC2) was identified as the predominant metabolite in plasma, urine, bile and feces after both oral and intravenous administrations to rats using HPLC-UV and HPLC-ESI/MS(n), and demethoxydeacetoxypseudolaric acid B (DDPB), a metabolite proposed to be the glucoside of PC2 (PC2G), as well as pseudolaric acid C (PC), pseudolaric acid A (PA), pseudolaric acid A O-beta-D glucopyranoside (PAG), pseudolaric acid B O-beta-D glucopyranoside (PBG) and deacetylpseudolaric acid A (DPA) originated from TDA could also be detected. It was demonstrated by tests that the metabolism of TDA is independent of intestinal microflora, and neither of pepsin and trypsin is in charge of metabolism of TDA, TDA is also stable in both pH environments of gastric tract and intestinal tract. The metabolites of TDA in whole blood in vitro incubation were found to be PC2, DDPB and PC2G, which demonstrated that the metabolic reaction of TDA in vivo is mainly occurred in blood and contributed to be the hydrolysis of plasma esterase to ester bond, as well as the glucosylation reaction. These results clarified the metabolic pathway of TDA for the first time, which is of great significance to the in vivo active form and acting mechanism research of P. kaempferi.
Simultaneous determination of seven major diterpenoids in Pseudolarix kaempferi by high-performance liquid chromatography DAD method.[Pubmed:17446030]
J Pharm Biomed Anal. 2007 Jul 27;44(3):730-6.
A reversed phase high-performance liquid chromatography method was established for the first time to simultaneously qualify the seven major diterpenoids in Pseudolarix kaempferi, namely pseudolaric acid B O-beta-D-glucopyranoside (1), pseudolaric acid C2 (2), pseudolaric acid C1 (3), deacetylpseudolaric acid A (4), pseudolaric acid A O-beta-D-glucopyranoside (5), pseudolaric acid B (6) and pseudolaric acid A (7). The optimal conditions of separation and detection were achieved on an Inertsil ODS-3 column with gradient elution of methanol and 0.5% aqueous acetic acid (v/v) at the flow rate of 0.6 ml min(-1) within 40 min and detection wavelength set at 262 nm. All calibration curves showed good linear regression (r2>0.9999) within test ranges. This method provided good accuracy with recoveries in the range of 94.3-106.1% and good precision with R.S.D.s of repeatability and intermediate precision less than 0.57% and 4.67%, respectively. The method was successfully applied to qualitative and quantitative determination of 20 P. kaempferi among the 54 samples collected from different areas. The results revealed that the commercial crude drugs were seriously confused and the developed HPLC assay could be used as a suitable qualitative and quantitative determination method for P. kaempferi.
