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Phlogacanthoside A

CAS# 830347-18-7

Phlogacanthoside A

Catalog No. BCN7540----Order now to get a substantial discount!

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Phlogacanthoside A:5mg Please Inquire In Stock
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Quality Control of Phlogacanthoside A

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Chemical structure

Phlogacanthoside A

3D structure

Chemical Properties of Phlogacanthoside A

Cas No. 830347-18-7 SDF Download SDF
PubChem ID 11454726 Appearance Powder
Formula C26H38O9 M.Wt 494.58
Type of Compound Diterpenoids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name (4R,4aS,7S,10aR,11bR)-7-hydroxy-4,8,11b-trimethyl-4-[[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxymethyl]-2,3,4a,5,6,7,10a,11-octahydro-1H-naphtho[2,1-f][1]benzofuran-9-one
SMILES CC1=C2C(CC3=C(C2O)CCC4C3(CCCC4(C)COC5C(C(C(C(O5)CO)O)O)O)C)OC1=O
Standard InChIKey USHSVQJEZJGRFF-CPHRPWCNSA-N
Standard InChI InChI=1S/C26H38O9/c1-12-18-15(34-23(12)32)9-14-13(19(18)28)5-6-17-25(2,7-4-8-26(14,17)3)11-33-24-22(31)21(30)20(29)16(10-27)35-24/h15-17,19-22,24,27-31H,4-11H2,1-3H3/t15-,16-,17-,19+,20-,21+,22-,24-,25+,26+/m1/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Phlogacanthoside A

The roots of Phlogacanthus curviflorus.

Biological Activity of Phlogacanthoside A

DescriptionPhlogacanthoside A is a natural product from Phlogacanthus curviflorus.

Protocol of Phlogacanthoside A

Structure Identification
J Nat Prod. 2005 Jan;68(1):86-9.

Two diterpenes and three diterpene glucosides from Phlogacanthus curviflorus.[Pubmed: 15679324 ]


METHODS AND RESULTS:
Two new diterpene lactones, phlogacantholides B (1) and C (2), and three new diterpene lactone glucosides, Phlogacanthoside A (3), phlogacanthoside B (4), and phlogacanthoside C (5), together with lupeol, beta-sitosterol, betulin, beta-daucosterol, (+)-syringaresinol, and (+)-syringaresinol-4-O-beta-D-glucopyranoside, were isolated from the roots of Phlogacanthus curviflorus. Their structures were elucidated by chemical and spectroscopic evidence.
CONCLUSIONS:
The structure, including the relative configuration of phlogacantholide B (1), was confirmed by X-ray crystallographic analysis of its diacetate (6).

Phlogacanthoside A Dilution Calculator

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Phlogacanthoside A Molarity Calculator

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Preparing Stock Solutions of Phlogacanthoside A

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.0219 mL 10.1096 mL 20.2192 mL 40.4384 mL 50.5479 mL
5 mM 0.4044 mL 2.0219 mL 4.0438 mL 8.0877 mL 10.1096 mL
10 mM 0.2022 mL 1.011 mL 2.0219 mL 4.0438 mL 5.0548 mL
50 mM 0.0404 mL 0.2022 mL 0.4044 mL 0.8088 mL 1.011 mL
100 mM 0.0202 mL 0.1011 mL 0.2022 mL 0.4044 mL 0.5055 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Phlogacanthoside A

Two diterpenes and three diterpene glucosides from Phlogacanthus curviflorus.[Pubmed:15679324]

J Nat Prod. 2005 Jan;68(1):86-9.

Two new diterpene lactones, phlogacantholides B (1) and C (2), and three new diterpene lactone glucosides, phlogacanthosides A (3), B (4), and C (5), together with lupeol, beta-sitosterol, betulin, beta-daucosterol, (+)-syringaresinol, and (+)-syringaresinol-4-O-beta-D-glucopyranoside, were isolated from the roots of Phlogacanthus curviflorus. Their structures were elucidated by chemical and spectroscopic evidence. The structure, including the relative configuration of phlogacantholide B (1), was confirmed by X-ray crystallographic analysis of its diacetate (6).

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