Orthosiphol ACAS# 142741-25-1 |
Quality Control & MSDS
Number of papers citing our products
Chemical structure
3D structure
| Cas No. | 142741-25-1 | SDF | Download SDF |
| PubChem ID | 15385858 | Appearance | Powder |
| Formula | C38H44O11 | M.Wt | 676.7 |
| Type of Compound | Diterpenoids | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| Chemical Name | [(2R,4R,4aS,4bS,5R,6S,7S,8aS,10R,10aR)-6,10-diacetyloxy-5-benzoyloxy-2-ethenyl-7,10a-dihydroxy-2,4b,8,8-tetramethyl-1-oxo-4,4a,5,6,7,8a,9,10-octahydro-3H-phenanthren-4-yl] benzoate | ||
| SMILES | CC(=O)OC1CC2C(C(C(C(C2(C3C1(C(=O)C(CC3OC(=O)C4=CC=CC=C4)(C)C=C)O)C)OC(=O)C5=CC=CC=C5)OC(=O)C)O)(C)C | ||
| Standard InChIKey | HIBFBUSEUDRQMX-OFUWLHILSA-N | ||
| Standard InChI | InChI=1S/C38H44O11/c1-8-36(6)20-25(48-32(42)23-15-11-9-12-16-23)29-37(7)26(19-27(46-21(2)39)38(29,45)34(36)44)35(4,5)30(41)28(47-22(3)40)31(37)49-33(43)24-17-13-10-14-18-24/h8-18,25-31,41,45H,1,19-20H2,2-7H3/t25-,26+,27-,28+,29-,30-,31+,36+,37+,38+/m1/s1 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
||
| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
||
| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
The roots of Orthosiphon
Orthosiphol A Dilution Calculator
Orthosiphol A Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 1.4778 mL | 7.3888 mL | 14.7776 mL | 29.5552 mL | 36.944 mL |
| 5 mM | 0.2956 mL | 1.4778 mL | 2.9555 mL | 5.911 mL | 7.3888 mL |
| 10 mM | 0.1478 mL | 0.7389 mL | 1.4778 mL | 2.9555 mL | 3.6944 mL |
| 50 mM | 0.0296 mL | 0.1478 mL | 0.2956 mL | 0.5911 mL | 0.7389 mL |
| 100 mM | 0.0148 mL | 0.0739 mL | 0.1478 mL | 0.2956 mL | 0.3694 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
Calcutta University
University of Minnesota
University of Maryland School of Medicine
University of Illinois at Chicago
The Ohio State University
University of Zurich
Harvard University
Colorado State University
Auburn University
Yale University
Worcester Polytechnic Institute
Washington State University
Stanford University
University of Leipzig
Universidade da Beira Interior
The Institute of Cancer Research
Heidelberg University
University of Amsterdam
University of Auckland
TsingHua University
The University of Michigan
Miami University
DRURY University
Jilin University
Fudan University
Wuhan University
Sun Yat-sen University
Universite de Paris
Deemed University
Auckland University
The University of Tokyo
Korea University
Featured Products
- Bergaptol-beta-glucopyranoside
Catalog No.:BCN8878
CAS No.:131623-13-7
- Astin C
Catalog No.:BCN8877
CAS No.:148057-23-2
- Neochlorogenic acid methyl ester
Catalog No.:BCN8860
CAS No.:123410-65-1
- Astin B
Catalog No.:BCN8858
CAS No.:151201-76-2
- Astin A
Catalog No.:BCN8851
CAS No.:151201-75-1
- Hydroxy-γ-sanshool
Catalog No.:BCN8849
CAS No.:78886-66-5
- Loureiriol
Catalog No.:BCN8843
CAS No.:479195-44-3
- (3R)-5,7-Dihydroxy-6-methyl-3-(4'-hydroxybenzyl)chroman-4-one
Catalog No.:BCN8842
CAS No.:84638-48-2
- Quercetin 3-O-rutinoside-1-2-O-rhamnoside
Catalog No.:BCN8820
CAS No.:55696-57-6
- Syringetin-3-O-rutinoside
Catalog No.:BCN8819
CAS No.:53430-50-5
- 6-Hydroxykaempferol 3-beta-rutinoside
Catalog No.:BCN8807
CAS No.:205527-00-0
- (+)-δ-Tocopherol
Catalog No.:BCN8805
CAS No.:119-13-1
New Products
- Gypenoside XIII
Catalog No.:BCN8927
CAS No.:80325-22-0
- Tigloylgomisin O
Catalog No.:BCN8880
CAS No.:130855-74-2
- Trachelogenin 4'-O-beta-gentiobioside
Catalog No.:BCN8881
CAS No.:106647-13-6
- Geoside
Catalog No.:BCN8882
CAS No.:585-90-0
- 3-O-methylellagic acid 4'-O-alpha-L-rhamnopyranoside
Catalog No.:BCN8884
CAS No.:51768-39-9
- Pieceid-2''-O-gallate
Catalog No.:BCN8885
CAS No.:105304-51-6
- Isolappaol A
Catalog No.:BCN8886
CAS No.:131400-96-9
- Isovalerylshikonin
Catalog No.:BCN8887
CAS No.:52387-14-1
- 2-Methoxyfuranoguaia-9-ene-8-one
Catalog No.:BCN8888
CAS No.:88010-62-2
- Notoptol
Catalog No.:BCN8889
CAS No.:88206-49-9
- Bruceantinol B
Catalog No.:BCN8890
CAS No.:1822332-33-1
- 1,2-Epoxy-10(14)-furanogermacren-6-one
Catalog No.:BCN8891
CAS No.:383368-24-9
Orthosiphol A from the aerial parts of Orthosiphon aristatus is putatively responsible for hypoglycemic effect via alpha-glucosidase inhibition.[Pubmed:25026708]
Nat Prod Commun. 2014 May;9(5):639-41.
An infusion of Orthosiphon aristatus has long been used for diabetes therapy; however, the active principles remained unknown. Herein, we report the identification of the putative agents responsible for this antidiabetic activity using an a-glucosidase-guided isolation. Four flavonoids named sinensetin (1), salvigenin (2), tetramethylscutellarein (3) and 3,7,4'-tri-O-methylkaempferol (4), together with a diterpenoid named Orthosiphol A (5), were characterized, based on analysis of their spectroscopic data. Flavonoids 3 and 4 inhibited yeast a-glucosidase with IC,o values of 6.34 and 0.75 mM, respectively, whereas Orthosiphol A (5) selectively inhibited intestinal maltase with an IC5o, value of 6.54 mM. A kinetic investigation of 5 indicated that it retarded maltase function in a noncompetitive manner.
Orthosiphol A,142741-25-1,Natural Products, buy Orthosiphol A , Orthosiphol A supplier , purchase Orthosiphol A , Orthosiphol A cost , Orthosiphol A manufacturer , order Orthosiphol A , high purity Orthosiphol A
