OplopanoneCAS# 1911-78-0 |
Quality Control & MSDS
Number of papers citing our products
Chemical structure
3D structure
| Cas No. | 1911-78-0 | SDF | Download SDF |
| PubChem ID | 10466745 | Appearance | Powder |
| Formula | C15H26O2 | M.Wt | 238.4 |
| Type of Compound | Sesquiterpenoids | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| Chemical Name | 1-[(1S,3aR,4R,7S,7aS)-4-hydroxy-4-methyl-7-propan-2-yl-1,2,3,3a,5,6,7,7a-octahydroinden-1-yl]ethanone | ||
| SMILES | CC(C)C1CCC(C2C1C(CC2)C(=O)C)(C)O | ||
| Standard InChIKey | WLXJHVQYKOJBBN-NJVJYBDUSA-N | ||
| Standard InChI | InChI=1S/C15H26O2/c1-9(2)11-7-8-15(4,17)13-6-5-12(10(3)16)14(11)13/h9,11-14,17H,5-8H2,1-4H3/t11-,12+,13+,14+,15+/m0/s1 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
| Description | 1. Oplopanone exhibits noteworthy anti-plasmodial activity against Plasmodium falciparum strain. |
| Targets | Antifection |
Oplopanone Dilution Calculator
Oplopanone Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 4.1946 mL | 20.9732 mL | 41.9463 mL | 83.8926 mL | 104.8658 mL |
| 5 mM | 0.8389 mL | 4.1946 mL | 8.3893 mL | 16.7785 mL | 20.9732 mL |
| 10 mM | 0.4195 mL | 2.0973 mL | 4.1946 mL | 8.3893 mL | 10.4866 mL |
| 50 mM | 0.0839 mL | 0.4195 mL | 0.8389 mL | 1.6779 mL | 2.0973 mL |
| 100 mM | 0.0419 mL | 0.2097 mL | 0.4195 mL | 0.8389 mL | 1.0487 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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A new sesquiterpenoid from the rhizomes of Homalomena sagittifolia.[Pubmed:21999629]
Nat Prod Res. 2012;26(9):850-8.
A new sesquiterpenoid, 1alpha,4beta,7beta-eudesmanetriol (1), was isolated together with the known compounds 1beta,4beta,7beta-eudesmanetriol (2) and Oplopanone (3) from the rhizomes of Homalomena sagittifolia. The structures of these compounds were determined by extensive spectral analyses. The compounds 1 and 2 inhibited growth of Pseudomonas stutzeri with a MIC value of 117 microM when evaluated for antibacterial activity using the minimum concentration assay. Both these compounds showed remarkable activities against acetylcholinesterase enzyme with IC(50) values ranging between 25 and 26 microM. The isolation of these sesquiterpenoids and their biological activities observed in this study support the reported traditional uses of H. sagittifolia for the treatment of microbial related diseases and central nervous system disorders.
Scopoletin from the flower buds of Magnolia fargesii inhibits protein glycation, aldose reductase, and cataractogenesis ex vivo.[Pubmed:20945129]
Arch Pharm Res. 2010 Sep;33(9):1317-23.
Five compounds previously known structures, scopoletin (1), northalifoline (2), stigmast-4-en-3-one (3), tiliroside (4), and Oplopanone (5) were obtained from the flower buds of Magnolia fargesii using chromatographic separation methods. The structures of 1-5 were identified by the interpretation of their spectroscopic data including 1D- and 2D-NMR as well as by comparison with reported values. Three compounds 1-3 were found from M. fargesii for the first time in this study. All the isolates (1-5) were subjected to in vitro bioassays to evaluate the inhibitory activity on advanced glycation end products formation and rat lens aldose reductase (RLAR). Compound 1 showed a remarkable inhibitory activity on advanced glycation end products formation with IC(50) value of 2.93 muM (aminoguanidine: 961 muM), and showed a significant RLAR inhibitory activity with IC(50) value of 22.5 muM (3.3-tetramethyleneglutaric acid: 28.7 muM). Compound 4 exhibited potent inhibitory activity against RLAR (IC(50) = 14.9 muM). In the further experiment ex vivo, cataractogenesis of rat lenses induced with xylose was significantly inhibited by compound 1 treatment.
Anti-plasmodial sesquiterpenoids from the African Reneilmia cincinnata.[Pubmed:10643672]
Phytochemistry. 1999 Nov;52(6):1095-9.
A new isodaucane sesquiterpenoid, 6,7,10-trihydoxyisodaucane, was isolated from the fruits of Reneilmia cincinnata, together with the known sesquiterpenoids oplodiol, Oplopanone, 5E,10(14)-germacradien-1 beta, 4 beta-diol, 1(10)E,5E-germacradien-4 alpha-ol and eudesman-1,4,7-triol. A large amount of 5-hydroxy-3,7,4'-trimethoxyflavone was also isolated. Their structures were established by NMR techniques using 1D and 2D experiments. Three of the known sesquirernenoids exhibited noteworthy anti-plasmodial activity against Plasmodium falciparum strains.
