MethylenedihydrotanshinquinoneCAS# 126979-81-5 |
Quality Control & MSDS
Number of papers citing our products
Chemical structure
3D structure
| Cas No. | 126979-81-5 | SDF | Download SDF |
| PubChem ID | 102004770 | Appearance | Red powder |
| Formula | C18H16O3 | M.Wt | 280.3 |
| Type of Compound | Diterpenoids | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| Chemical Name | (1R)-1-methyl-6-methylidene-2,7,8,9-tetrahydro-1H-naphtho[1,2-g][1]benzofuran-10,11-dione | ||
| SMILES | CC1COC2=C1C(=O)C(=O)C3=C2C=CC4=C3CCCC4=C | ||
| Standard InChIKey | UXXYCZFYFKWTPQ-JTQLQIEISA-N | ||
| Standard InChI | InChI=1S/C18H16O3/c1-9-4-3-5-12-11(9)6-7-13-15(12)17(20)16(19)14-10(2)8-21-18(13)14/h6-7,10H,1,3-5,8H2,2H3/t10-/m0/s1 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
||
| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
||
| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
| Description | 1. Methylenedihydrotanshinquinone has cytotoxic activity. |
Methylenedihydrotanshinquinone Dilution Calculator
Methylenedihydrotanshinquinone Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 3.5676 mL | 17.838 mL | 35.6761 mL | 71.3521 mL | 89.1902 mL |
| 5 mM | 0.7135 mL | 3.5676 mL | 7.1352 mL | 14.2704 mL | 17.838 mL |
| 10 mM | 0.3568 mL | 1.7838 mL | 3.5676 mL | 7.1352 mL | 8.919 mL |
| 50 mM | 0.0714 mL | 0.3568 mL | 0.7135 mL | 1.427 mL | 1.7838 mL |
| 100 mM | 0.0357 mL | 0.1784 mL | 0.3568 mL | 0.7135 mL | 0.8919 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
Calcutta University
University of Minnesota
University of Maryland School of Medicine
University of Illinois at Chicago
The Ohio State University
University of Zurich
Harvard University
Colorado State University
Auburn University
Yale University
Worcester Polytechnic Institute
Washington State University
Stanford University
University of Leipzig
Universidade da Beira Interior
The Institute of Cancer Research
Heidelberg University
University of Amsterdam
University of Auckland
TsingHua University
The University of Michigan
Miami University
DRURY University
Jilin University
Fudan University
Wuhan University
Sun Yat-sen University
Universite de Paris
Deemed University
Auckland University
The University of Tokyo
Korea University
- Sar-[D-Phe8]-des-Arg9-Bradykinin
Catalog No.:BCC5996
CAS No.:126959-88-4
- LGX818
Catalog No.:BCC4184
CAS No.:1269440-17-6
- MK 1903
Catalog No.:BCC6242
CAS No.:1268882-43-4
- 3-Methoxy-5-heneicosylphenol
Catalog No.:BCN6147
CAS No.:126882-76-6
- Ssioriside
Catalog No.:BCN6146
CAS No.:126882-53-9
- MC 1046
Catalog No.:BCC1733
CAS No.:126860-83-1
- (-)-JQ1
Catalog No.:BCC3603
CAS No.:1268524-71-5
- Bromodomain Inhibitor, (+)-JQ1
Catalog No.:BCC1132
CAS No.:1268524-70-4
- 8alpha-Acetoxyarglabin
Catalog No.:BCN7315
CAS No.:126829-70-7
- 13-Acetoxy-3beta-hydroxygermacra-1(10)E,4E,7(11)-trien-12,6alpha-olide
Catalog No.:BCN7314
CAS No.:126829-66-1
- 5,7,3'-Trihydroxy-4'-methoxy-8-prenylflavanone
Catalog No.:BCN1590
CAS No.:1268140-15-3
- Ulipristal acetate
Catalog No.:BCC4068
CAS No.:126784-99-4
- Tetrahydro tanshinone I
Catalog No.:BCN2602
CAS No.:126979-84-8
- CDK inhibitor II
Catalog No.:BCC1464
CAS No.:1269815-17-9
- 5-Hydroxy-1,7-bis(4-hydroxyphenyl)heptan-3-yl acetate
Catalog No.:BCN6586
CAS No.:1269839-24-8
- 1-(3,4-Dihydroxyphenyl)-7-(4-hydroxyphenyl)heptane-3,5-diyl diacetate
Catalog No.:BCN6572
CAS No.:1269839-26-0
- Locustatachykinin I
Catalog No.:BCC5926
CAS No.:126985-97-5
- Hydroxyurea
Catalog No.:BCC4912
CAS No.:127-07-1
- Sodium acetate
Catalog No.:BCC7587
CAS No.:127-09-3
- Taraxerol
Catalog No.:BCN6148
CAS No.:127-22-0
- Pimaric acid
Catalog No.:BCN6149
CAS No.:127-27-5
- Lasiocarpine N-oxide
Catalog No.:BCN2002
CAS No.:127-30-0
- Lutein
Catalog No.:BCN6151
CAS No.:127-40-2
- Vitamin A Acetate
Catalog No.:BCC4748
CAS No.:127-47-9
From Bioprofiling and Characterization to Bioquantification of Natural Antibiotics by Direct Bioautography Linked to High-Resolution Mass Spectrometry: Exemplarily Shown for Salvia miltiorrhiza Root.[Pubmed:27766834]
Anal Chem. 2016 Nov 15;88(22):10979-10986.
Phytochemicals are promising agents in the development of new antibiotics. A streamlined strategy for rapid screening and reliable characterization of antibiotics in botanicals was demonstrated in contrast to the commonly applied chromatographic column fractionation followed by microtiter plate assay. Modern direct bioautography hyphenated to structure elucidation techniques is a straightforward bioanalytical tool, especially if microbiological assays were taken into account. At one go, lipophilic antimicrobials in Salvia miltiorrhiza root samples were analyzed using high-performance thin-layer chromatography (HPTLC) in direct combination with Aliivibrio fischeri and Bacillus subtilis bioassays. The most intense antimicrobials were characterized via HPTLC-high-resolution mass spectrometry. As proof of this streamlined strategy, dihydrotanshinone, cryptotanshinone, and tanshinone IIA were identified and also compared with a reference. Two further antimicrobial zones in the bioautograms were tentatively assigned to be methylenetanshinquinone and tetrahydrotanshinone I (or its structural isomer Methylenedihydrotanshinquinone). In another run, a validation study was performed for the bioquantification of ciprofloxacin and marbofloxacin via HPTLC-Bacillus subtilis. This pointed out the improved quality of the performance that was reached. Cryptotanshinone was biologically quantified in two S. miltiorrhiza root samples. Antimicrobials without an available reference standard were calculated as cryptotanshinone-bioequivalents. The results were of relevance, as 1 ng of cryptotanshinone was calculated to be bioequivalent to 0.6 ng and 2 ng of the synthetic antibiotics, ciprofloxacin and marbofloxacin, respectively. For the first time, quantitative direct bioautography via HPTLC-B. subtilis was shown as a reliable tool for streamlined bioprofiling of complex samples.
