Malvidin-3-O-glucoside chlorideCAS# 7228-78-6 |
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| Cas No. | 7228-78-6 | SDF | Download SDF |
| PubChem ID | 65178 | Appearance | Red-black powder |
| Formula | C23H25ClO12 | M.Wt | 528.9 |
| Type of Compound | Flavonoids | Storage | Desiccate at -20°C |
| Synonyms | Oenin chloride | ||
| Solubility | Soluble in methan | ||
| Chemical Name | (3R,4S,5S,6R)-2-[5,7-dihydroxy-2-(4-hydroxy-3,5-dimethoxyphenyl)chromenylium-3-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol;chloride | ||
| SMILES | COC1=CC(=CC(=C1O)OC)C2=C(C=C3C(=CC(=CC3=[O+]2)O)O)OC4C(C(C(C(O4)CO)O)O)O.[Cl-] | ||
| Standard InChIKey | YDIKCZBMBPOGFT-QDWAHGIWSA-N | ||
| Standard InChI | InChI=1S/C23H24O12.ClH/c1-31-14-3-9(4-15(32-2)18(14)27)22-16(7-11-12(26)5-10(25)6-13(11)33-22)34-23-21(30)20(29)19(28)17(8-24)35-23;/h3-7,17,19-21,23-24,28-30H,8H2,1-2H3,(H2-,25,26,27);1H/t17-,19-,20+,21-,23?;/m1./s1 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
1 Erica sp. 2 Malva sp. 3 Phaseolus sp. 4 Primula sp. 5 Rhododendron sp. 6 Vaccinium sp. 7 Vitis sp.
| Description | 1. Malvidin 3-glucoside has antioxidant activity, alone is not oxidized in the presence of grape polyphenol oxidase. 2. Malvidin 3-glucoside's color stabilization at a higher pH can be explained by self-aggregation of the flavylium cation and copigmentation with the Z-chalcone form. |
Malvidin-3-O-glucoside chloride Dilution Calculator
Malvidin-3-O-glucoside chloride Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 1.8907 mL | 9.4536 mL | 18.9072 mL | 37.8143 mL | 47.2679 mL |
| 5 mM | 0.3781 mL | 1.8907 mL | 3.7814 mL | 7.5629 mL | 9.4536 mL |
| 10 mM | 0.1891 mL | 0.9454 mL | 1.8907 mL | 3.7814 mL | 4.7268 mL |
| 50 mM | 0.0378 mL | 0.1891 mL | 0.3781 mL | 0.7563 mL | 0.9454 mL |
| 100 mM | 0.0189 mL | 0.0945 mL | 0.1891 mL | 0.3781 mL | 0.4727 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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Malvidin 3-O-β-glucopyranoside is a natural colorant found in bilberries and other fruits and flowers. It is produced from natural sources (extraction processes). The product will release hydrochloric acid in water. The product is hygroscopic.The chemical formula is C23H25O12Cl. The molecular weight is 528.9 g/mol. The product belongs to the anthocyanins, which is a class of natural chemicals belonging to the flavonoids. It is highly water-soluble and is easily degraded by hydrolysis and /or hydrogenation at temperatures >40°C.The product shall be dark red /purple in colour, and shall normally be powdered.The product has a purity >98% as detected by high- performance liquid chromatography (HPLC) connected to UV /Vis detector at 280nm and 520nm. The rest is impurities of other anthocyanins, flavonoids or polyphenols.The product should be kept in darkness and at low temperatures for storage more than a few days (< -5°C).
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Anthocyanin Interactions with DNA: Intercalation, Topoisomerase I Inhibition and Oxidative Reactions.[Pubmed:19924259]
J Food Biochem. 2008 Sep 23;32(5):576-596.
Anthocyanins and their aglycone anthocyanidins are pigmented flavonoids found in significant amounts in many commonly consumed foods. They exhibit a complex chemistry in aqueous solution, which makes it difficult to study their chemistry under physiological conditions. Here we used a gel electrophoresis assay employing supercoiled DNA plasmid to examine the ability of these compounds (1) to intercalate DNA, (2) to inhibit human topoisomerase I through both inhibition of plasmid relaxation activity (catalytic inhibition) and stabilization of the cleavable DNA-topoisomerase complex (poisoning), and (3) to inhibit or enhance oxidative single-strand DNA nicking. We found no evidence of DNA intercalation by anthocyan(id)ins in the physiological pH range for any of the compounds used in this study-cyanidin chloride, cyanidin 3-O-glucoside, cyanidin 3,5-O-diglucoside, malvidin 3-O-glucoside and luteolinidin chloride. The anthocyanins inhibited topoisomerase relaxation activity only at high concentrations (> 50 muM) and we could find no evidence of topoisomerase I cleavable complex stabilization by these compounds. However, we observed that all of the anthocyan(id)ins used in this study were capable of inducing significant oxidative DNA strand cleavage (nicking) in the presence of 1 mM DTT (dithiothreitol), while the free radical scavenger, DMSO, at concentrations typically used in similar studies, completely inhibited DNA nicking. Finally, we propose a mechanism to explain the anthocyan(id)in induced oxidative DNA cleavage observed under our experimental conditions.
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