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Maingayone

CAS# 271585-66-1

Maingayone

Catalog No. BCN0990----Order now to get a substantial discount!

Product Name & Size Price Stock
Maingayone:10mg $308 In stock
Maingayone:20mg Please Inquire Instock
Maingayone:50mg Please Inquire Instock
Maingayone:100mg Please Inquire Instock

Quality Control of Maingayone

Number of papers citing our products

Chemical structure

Maingayone

Chemical Properties of Maingayone

Cas No. 271585-66-1 SDF Download SDF
PubChem ID N/A Appearance Oil
Formula C42H52O9 M.Wt 700.9
Type of Compound Phenols Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Maingayone

The herbs of Curcuma wenyujin Y.H.Chen & C.Ling

Maingayone Dilution Calculator

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Maingayone Molarity Calculator

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Preparing Stock Solutions of Maingayone

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 1.4267 mL 7.1337 mL 14.2674 mL 28.5347 mL 35.6684 mL
5 mM 0.2853 mL 1.4267 mL 2.8535 mL 5.7069 mL 7.1337 mL
10 mM 0.1427 mL 0.7134 mL 1.4267 mL 2.8535 mL 3.5668 mL
50 mM 0.0285 mL 0.1427 mL 0.2853 mL 0.5707 mL 0.7134 mL
100 mM 0.0143 mL 0.0713 mL 0.1427 mL 0.2853 mL 0.3567 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Maingayone

New arylalkanones from Horsfieldia macrobotrys, effective antidiabetic agents concomitantly inhibiting alpha-glucosidase and free radicals.[Pubmed:26343830]

Bioorg Med Chem Lett. 2015 Oct 15;25(20):4529-33.

In search of effective antidiabetic agents having therapeutic effect by inhibiting alpha-glucosidase and preventive effect by scavenging free radicals, Horsfieldia macrobotrys showed promising bioactivity required for the proposed criteria. Bioassay-guided isolation of the stem bark extract resulted in two new arylalkanones named horsfieldone A (1) and Maingayone D (2), together with a new flavanone C-glucoside named 8-C-beta-d-glucopyranosylpinocembrin (3). Their structures and stereochemistry were determined by spectroscopic techniques as well as Mosher's method. Of isolated compounds, Maingayone D (2) was the most potent inhibitors against both alpha-glucosidases and free radicals. The presence of additional phenolic moieties in 2 clearly indicated their critical roles in inhibitory effects. Further investigation on mechanism underlying alpha-glucosidase inhibition indicated that Maingayone D (2) could retard the enzyme function by both competitive and noncompetitive manners.

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