GlobularinCAS# 1399-49-1 |
Quality Control & MSDS
Number of papers citing our products
Chemical structure
3D structure
| Cas No. | 1399-49-1 | SDF | Download SDF |
| PubChem ID | 21603201 | Appearance | Powder |
| Formula | C24H28O11 | M.Wt | 492.5 |
| Type of Compound | Iridoids | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| Chemical Name | [(1S,2S,4S,5S,6R,10S)-5-hydroxy-10-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3,9-dioxatricyclo[4.4.0.02,4]dec-7-en-2-yl]methyl (E)-3-phenylprop-2-enoate | ||
| SMILES | C1=CC=C(C=C1)C=CC(=O)OCC23C4C(C=COC4OC5C(C(C(C(O5)CO)O)O)O)C(C2O3)O | ||
| Standard InChIKey | SCIGYBYAZUFDLA-LUVHZPKESA-N | ||
| Standard InChI | InChI=1S/C24H28O11/c25-10-14-18(28)19(29)20(30)23(33-14)34-22-16-13(8-9-31-22)17(27)21-24(16,35-21)11-32-15(26)7-6-12-4-2-1-3-5-12/h1-9,13-14,16-23,25,27-30H,10-11H2/b7-6+/t13-,14-,16-,17+,18-,19+,20-,21+,22+,23+,24-/m1/s1 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
| Description | 1. Globularin has hypoglycaemic and hypolipidemic activities in normal and streptozotocin-induced diabetic rats. |
Globularin Dilution Calculator
Globularin Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 2.0305 mL | 10.1523 mL | 20.3046 mL | 40.6091 mL | 50.7614 mL |
| 5 mM | 0.4061 mL | 2.0305 mL | 4.0609 mL | 8.1218 mL | 10.1523 mL |
| 10 mM | 0.203 mL | 1.0152 mL | 2.0305 mL | 4.0609 mL | 5.0761 mL |
| 50 mM | 0.0406 mL | 0.203 mL | 0.4061 mL | 0.8122 mL | 1.0152 mL |
| 100 mM | 0.0203 mL | 0.1015 mL | 0.203 mL | 0.4061 mL | 0.5076 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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Aragoside and iridoid glucosides from Aragoa cundinamarcensis.[Pubmed:12943770]
Phytochemistry. 2003 Sep;64(2):529-33.
From the water-soluble part of an extract of Aragoa cundinamarcensis were isolated seven iridoid glucosides, namely aucubin, catalpol, rehmannioside D, Globularin, gardoside methyl ester, epiloganin and mussaenoside. The main glycoside isolated, however, was a new caffeoyl phenylethanoid triglycoside, named aragoside, containing two beta-gluco- and one alpha-arabinopyranosyl moieties which constituted almost 5% of the dry weight of the plant. Finally, sorbitol was found to be the main carbohydrate constituent of the plant. This distinctive combination of compounds is very similar to that reported from some species of Plantago. The present findings therefore support the results from a recently published molecular phylogenetic study of plastid and nuclear ribosomal DNA sequences, where Aragoa was found to be the closest relative to Plantago so far discovered.
Iridoid glucosides from the aerial parts of Globularia alypum L. (Globulariaceae).[Pubmed:16394555]
Chem Pharm Bull (Tokyo). 2006 Jan;54(1):85-8.
From the hydromethanolic extract of the aerial parts of Globularia alypum grown in Morocco, a new chlorinated iridoid glucoside, globularioside has been isolated beside 5 known iridoid glycosides, Globularin, globularicisin, globularidin, Globularinin and globularimin. This is the first report of a chlorinated iridoid in G. alypum and in the Globulareaceae. Unlike all other known 7-chlorinated iridoid glucosides where the chlorine atom exhibits an alpha configuration, globularioside incorporate the chlorine atom as a 7beta substituent. The structures of the isolated compounds were established on the basis of ESI-MS, MS-MS, 1D and 2D NMR spectral analysis.
[Studies on chemical constituents from herb of Hemiphragma heterophyllum].[Pubmed:15706915]
Zhongguo Zhong Yao Za Zhi. 2004 Jun;29(6):528-31.
OBJECTIVE: To study the chemical constituents from Hemiphragma heterophyllum. METHOD: The constituents were isolated and purified by chromatographic technology and their structures were elucidated by physico-chemical evidence and spectral data. RESULT: Eight compounds were isolated and identified as hemiphroside C (I), plantainoside E (II), hemiphroside A (III), acetoside (IV), Globularin (V), 10-(Z)-cinnamoyl-catapol (VI), iso-scrophularioside (VII), cinnamic acid (VIII). CONCLUSION: Compound I was a new phenylethanoid glucoside and compounds II and VI were isolated for the first time from this plant.
