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Di-Dnp-L-Lysine

CAS# 1655-49-8

Di-Dnp-L-Lysine

Catalog No. BCC8939----Order now to get a substantial discount!

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Di-Dnp-L-Lysine:5mg Please Inquire In Stock
Di-Dnp-L-Lysine:10mg Please Inquire In Stock
Di-Dnp-L-Lysine:20mg Please Inquire In Stock
Di-Dnp-L-Lysine:50mg Please Inquire In Stock

Quality Control of Di-Dnp-L-Lysine

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Chemical structure

Di-Dnp-L-Lysine

3D structure

Chemical Properties of Di-Dnp-L-Lysine

Cas No. 1655-49-8 SDF Download SDF
PubChem ID 96818 Appearance Powder
Formula C18H18N6O10 M.Wt 478.4
Type of Compound N/A Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name (2S)-2,6-bis(2,4-dinitroanilino)hexanoic acid
SMILES C1=CC(=C(C=C1[N+](=O)[O-])[N+](=O)[O-])NCCCCC(C(=O)O)NC2=C(C=C(C=C2)[N+](=O)[O-])[N+](=O)[O-]
Standard InChIKey XFVSVNWYIWINEC-HNNXBMFYSA-N
Standard InChI InChI=1S/C18H18N6O10/c25-18(26)15(20-14-7-5-12(22(29)30)10-17(14)24(33)34)3-1-2-8-19-13-6-4-11(21(27)28)9-16(13)23(31)32/h4-7,9-10,15,19-20H,1-3,8H2,(H,25,26)/t15-/m0/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Di-Dnp-L-Lysine Dilution Calculator

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Di-Dnp-L-Lysine Molarity Calculator

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Preparing Stock Solutions of Di-Dnp-L-Lysine

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.0903 mL 10.4515 mL 20.903 mL 41.806 mL 52.2575 mL
5 mM 0.4181 mL 2.0903 mL 4.1806 mL 8.3612 mL 10.4515 mL
10 mM 0.209 mL 1.0452 mL 2.0903 mL 4.1806 mL 5.2258 mL
50 mM 0.0418 mL 0.209 mL 0.4181 mL 0.8361 mL 1.0452 mL
100 mM 0.0209 mL 0.1045 mL 0.209 mL 0.4181 mL 0.5226 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Di-Dnp-L-Lysine

Antigenic modulation of the cytophilic binding of guinea-pig IgG and IgM antibodies to homologous macrophages.[Pubmed:86509]

Immunology. 1979 Apr;36(4):659-70.

The cytophilic binding of immune complexes by peritoneal exudate cells (PEC) from adjuvant-stimulated guinea-pigs was studied using 125I-labelled guinea-pig IgG1, IgG2 and IgM antibodies to the dinitrophenyl (DNP) group. The influence of hapten density upon cytophilic activity was studied by the addition of DNP-conjugated antigens to antibody in 2-200 molar ratios of DNP:antibody. Only IgG2 binding was enhanced by immune complex formation, and the increased binding of IgG2 anti-DNP was dependent on the number of DNP determinants per antigen molecule. Cytophilic activity with epsilon-DNP-L-lysine (DNP-LYS), alpha,epsilon-Di-Dnp-L-Lysine (DNP-LYS-DNP), or DNP1-8-BSA was no greater than that seen in the absence of hapten. Increased cytophilic binding was noted only with DNP20-41-BSA. The binding of IgG2 and IgG2 anti-DNP:DNP-bovine serum albumin (BSA) complexes was inhibited by monomeric IgG2. The relative cytophilic capacities of guinea-pig immunoglobulins appeared as follows: IgG greater than IgG1 greater than IgM. IgG1 and IgM binding of DNP conjugates did not enhance their cytophilic activity; therefore, IgG1 and IgM cytophilic binding to PEC was considered biologically insignificant. This investigation provides further evidence that cytophilic binding of immune complexes to macrophages is due to the co-operative action of multiple Fc sites rather than a conformational change in the IgG2 antibodies, and serum proteins, notably complement components, can alter the binding and/or phagocytosis of IgG2 anti-DNP:DNP-BSA complexes.

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