Home >> Research Area >>Natural Products>>Miscellaneous>> Deoxynojirimycin hydrochloride

Deoxynojirimycin hydrochloride

CAS# 73285-50-4

Deoxynojirimycin hydrochloride

Catalog No. BCN2626----Order now to get a substantial discount!

Product Name & Size Price Stock
Deoxynojirimycin hydrochloride:5mg Please Inquire In Stock
Deoxynojirimycin hydrochloride:10mg Please Inquire In Stock
Deoxynojirimycin hydrochloride:20mg Please Inquire In Stock
Deoxynojirimycin hydrochloride:50mg Please Inquire In Stock
Related Products

Quality Control of Deoxynojirimycin hydrochloride

Number of papers citing our products

Chemical structure

Deoxynojirimycin hydrochloride

3D structure

Chemical Properties of Deoxynojirimycin hydrochloride

Cas No. 73285-50-4 SDF Download SDF
PubChem ID 13018787 Appearance Powder
Formula C6H14ClNO4 M.Wt 199.6
Type of Compound Miscellaneous Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name (2R,3R,4R,5S)-2-(hydroxymethyl)piperidine-3,4,5-triol;hydrochloride
SMILES C1C(C(C(C(N1)CO)O)O)O.Cl
Standard InChIKey ZJIHMALTJRDNQI-VFQQELCFSA-N
Standard InChI InChI=1S/C6H13NO4.ClH/c8-2-3-5(10)6(11)4(9)1-7-3;/h3-11H,1-2H2;1H/t3-,4+,5-,6-;/m1./s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Deoxynojirimycin hydrochloride

The root barks of Morus alba L.

Biological Activity of Deoxynojirimycin hydrochloride

Description1.1-Deoxynojirimycin hydrochloride shows inhibitory activity against α-glucosidases, inhibitors of α-glucosidase are promising candidates for the development of antitype II diabetics and anti-AIDS drugs.

Deoxynojirimycin hydrochloride Dilution Calculator

Concentration (start)
x
Volume (start)
=
Concentration (final)
x
Volume (final)
 
 
 
C1
V1
C2
V2

calculate

Deoxynojirimycin hydrochloride Molarity Calculator

Mass
=
Concentration
x
Volume
x
MW*
 
 
 
g/mol

calculate

Preparing Stock Solutions of Deoxynojirimycin hydrochloride

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 5.01 mL 25.0501 mL 50.1002 mL 100.2004 mL 125.2505 mL
5 mM 1.002 mL 5.01 mL 10.02 mL 20.0401 mL 25.0501 mL
10 mM 0.501 mL 2.505 mL 5.01 mL 10.02 mL 12.5251 mL
50 mM 0.1002 mL 0.501 mL 1.002 mL 2.004 mL 2.505 mL
100 mM 0.0501 mL 0.2505 mL 0.501 mL 1.002 mL 1.2525 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

Organizitions Citing Our Products recently

 
 
 

Calcutta University

University of Minnesota

University of Maryland School of Medicine

University of Illinois at Chicago

The Ohio State University

University of Zurich

Harvard University

Colorado State University

Auburn University

Yale University

Worcester Polytechnic Institute

Washington State University

Stanford University

University of Leipzig

Universidade da Beira Interior

The Institute of Cancer Research

Heidelberg University

University of Amsterdam

University of Auckland
TsingHua University
TsingHua University
The University of Michigan
The University of Michigan
Miami University
Miami University
DRURY University
DRURY University
Jilin University
Jilin University
Fudan University
Fudan University
Wuhan University
Wuhan University
Sun Yat-sen University
Sun Yat-sen University
Universite de Paris
Universite de Paris
Deemed University
Deemed University
Auckland University
Auckland University
The University of Tokyo
The University of Tokyo
Korea University
Korea University
Featured Products
New Products
 

References on Deoxynojirimycin hydrochloride

Chlorogenic acid derivatives with alkyl chains of different lengths and orientations: potent alpha-glucosidase inhibitors.[Pubmed:18783210]

J Med Chem. 2008 Oct 9;51(19):6188-94.

Alpha-glucosidases play important roles in the digestion of carbohydrates and biosynthesis of viral envelope glycoproteins. Inhibitors of alpha-glucosidase are promising candidates for the development of antitype II diabetics and anti-AIDS drugs. Here, we report the synthesis and alpha-glucosidase inhibitory activity of mono- and diketal/acetal derivatives of chlorogenic acid. The diketal derivatives showed more potent inhibitory activity than the monoketals. The 1,7-(5-nonanone) 3,4-(5-nonanone)-chlorogenic acid diketal showed remarkable inhibitory activity against alpha-glucosidases with potency better than that of 1-Deoxynojirimycin hydrochloride. Four diasteremers of pelargonaldehyde diacetal and two of monoacetal derivatives of chlorogenic acid were synthesized in this study. They showed significant potent inhibition similar to or more potent than the ketal counterparts. Acetals with the alkyl chain oriented toward position 2 of chlorogenic acid showed more potent activity than those oriented toward position 6.

Description

1-Deoxynojirimycin hydrochloride (Duvoglustat hydrochloride) is a potent and orally active α-glucosidase inhibitor. 1-Deoxynojirimycin hydrochloride suppresses postprandial blood glucose and is widely used for diabetes mellitus. 1-Deoxynojirimycin hydrochloride possesses antihyperglycemic, anti-obesity, and antiviral features.

Keywords:

Deoxynojirimycin hydrochloride,73285-50-4,Natural Products, buy Deoxynojirimycin hydrochloride , Deoxynojirimycin hydrochloride supplier , purchase Deoxynojirimycin hydrochloride , Deoxynojirimycin hydrochloride cost , Deoxynojirimycin hydrochloride manufacturer , order Deoxynojirimycin hydrochloride , high purity Deoxynojirimycin hydrochloride

Online Inquiry for:

      Fill out the information below

      • Size:Qty: - +

      * Required Fields

                                      Result: