Cudraxanthone LCAS# 135541-40-1 |
Quality Control & MSDS
Number of papers citing our products
Chemical structure
3D structure
| Cas No. | 135541-40-1 | SDF | Download SDF |
| PubChem ID | 11486277 | Appearance | Yellow powder |
| Formula | C23H24O6 | M.Wt | 396.4 |
| Type of Compound | Xanthones | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| Chemical Name | 1,3,6,7-tetrahydroxy-2-(2-methylbut-3-en-2-yl)-5-(3-methylbut-2-enyl)xanthen-9-one | ||
| SMILES | CC(=CCC1=C2C(=CC(=C1O)O)C(=O)C3=C(C(=C(C=C3O2)O)C(C)(C)C=C)O)C | ||
| Standard InChIKey | LVKPSBFBKBJJOB-UHFFFAOYSA-N | ||
| Standard InChI | InChI=1S/C23H24O6/c1-6-23(4,5)18-14(24)10-16-17(21(18)28)20(27)13-9-15(25)19(26)12(22(13)29-16)8-7-11(2)3/h6-7,9-10,24-26,28H,1,8H2,2-5H3 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
| Description | 1. Cudraxanthone L shows the significant hepatoprotective effect on nitrofurantoin-induced cytotoxicity in human liver-derived Hep G2 cells. |
Cudraxanthone L Dilution Calculator
Cudraxanthone L Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 2.5227 mL | 12.6135 mL | 25.227 mL | 50.4541 mL | 63.0676 mL |
| 5 mM | 0.5045 mL | 2.5227 mL | 5.0454 mL | 10.0908 mL | 12.6135 mL |
| 10 mM | 0.2523 mL | 1.2614 mL | 2.5227 mL | 5.0454 mL | 6.3068 mL |
| 50 mM | 0.0505 mL | 0.2523 mL | 0.5045 mL | 1.0091 mL | 1.2614 mL |
| 100 mM | 0.0252 mL | 0.1261 mL | 0.2523 mL | 0.5045 mL | 0.6307 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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Prenylated xanthones from the root bark of Cudrania tricuspidata.[Pubmed:17608532]
J Nat Prod. 2007 Jul;70(7):1207-9.
Four new prenylated xanthones, cudratricusxanthones J-M (1-4), were isolated from the CH2Cl2-soluble extract of the root bark of Cudrania tricuspidata, along with four known prenylated xanthones, isocudraxanthone K (5), cudraxanthone C (6), cudratricusxanthone A (7), and Cudraxanthone L (8), and three known prenylated flavonoids, cudraflavone A (9), cudraflavanone A (10), and cudraflavone B (11). The structures of compounds 1-4 were elucidated using spectroscopic methods. Cudratricusxanthone A (7), cudraflavanone A (10), and cudraflavone B (11) showed moderate inhibitory effects on mouse brain monoamine oxidase (MAO) with IC50 values of 88.3, 89.7, and 80.0 microM, respectively.
Cytotoxic xanthones from Cudrania tricuspidata.[Pubmed:15787460]
J Nat Prod. 2005 Mar;68(3):456-8.
The new isoprenylated tetrahydroxyxanthone, 2,3,6,8-tetrahydroxy-1-(3-methylbut-2-enyl)-5-(2-methylbut-3-en-2-yl)-9H-xanthen- 9-one (1), was isolated from the root bark of Cudrania tricuspidata together with macluraxanthone B (2) and Cudraxanthone L (3), which were fully characterized by NMR spectroscopic and X-ray crystallographic analyses.
Hepatoprotective constituents of Cudrania tricuspidata.[Pubmed:15742807]
Arch Pharm Res. 2005 Jan;28(1):44-8.
Phytochemical investigation of the MeOH extract of the root barks of Cudrania tricuspidata Bureau (Moraceae), as guided by hepatoprotective activity in vitro, furnished four isoprenylated xanthones, cudratricusxanthone A (1), Cudraxanthone L (2), cudratricusxanthone E (3), and macluraxanthone B (4). All of these compounds showed the significant hepatoprotective effect on tacrine-induced cytotoxicity in human liver-derived Hep G2 cells. Compounds 1, 2, and 4 also exhibited the significant hepatoprotective effect on nitrofurantoin-induced cytotoxicity in human liver-derived Hep G2 cells.
