Coccinic acidCAS# 107783-45-9 |
Quality Control & MSDS
Number of papers citing our products
Chemical structure
3D structure
| Cas No. | 107783-45-9 | SDF | Download SDF |
| PubChem ID | 124845081 | Appearance | Powder |
| Formula | C30H46O3 | M.Wt | 454.7 |
| Type of Compound | Triterpenoids | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| Chemical Name | (E,6R)-2-methyl-6-[(5R,8S,10S,13R,14S,17R)-4,4,10,13,14-pentamethyl-3-oxo-1,2,5,6,7,8,12,15,16,17-decahydrocyclopenta[a]phenanthren-17-yl]hept-2-enoic acid | ||
| SMILES | CC(CCC=C(C)C(=O)O)C1CCC2(C1(CC=C3C2CCC4C3(CCC(=O)C4(C)C)C)C)C | ||
| Standard InChIKey | HGNBFRRLBCNAAD-FUILTSNHSA-N | ||
| Standard InChI | InChI=1S/C30H46O3/c1-19(9-8-10-20(2)26(32)33)21-13-17-30(7)23-11-12-24-27(3,4)25(31)15-16-28(24,5)22(23)14-18-29(21,30)6/h10,14,19,21,23-24H,8-9,11-13,15-18H2,1-7H3,(H,32,33)/b20-10+/t19-,21-,23-,24+,28-,29-,30+/m1/s1 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
||
| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
||
| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
| Description | 1. Mixture of coccinic acid and anwuweizonic acid shows significant inhibitory activity against human decidual cells and rat luteal cells in vitro, suggests that it has antifertility activity. 2. Coccinic acid shows inhibitory effects against colorectal carcinoma HCT-15 and oral epithelial cell line KB-3-1. |
| Targets | Estrogen receptor | Progestogen receptor |
Coccinic acid Dilution Calculator
Coccinic acid Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 2.1993 mL | 10.9963 mL | 21.9925 mL | 43.985 mL | 54.9813 mL |
| 5 mM | 0.4399 mL | 2.1993 mL | 4.3985 mL | 8.797 mL | 10.9963 mL |
| 10 mM | 0.2199 mL | 1.0996 mL | 2.1993 mL | 4.3985 mL | 5.4981 mL |
| 50 mM | 0.044 mL | 0.2199 mL | 0.4399 mL | 0.8797 mL | 1.0996 mL |
| 100 mM | 0.022 mL | 0.11 mL | 0.2199 mL | 0.4399 mL | 0.5498 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
Calcutta University
University of Minnesota
University of Maryland School of Medicine
University of Illinois at Chicago
The Ohio State University
University of Zurich
Harvard University
Colorado State University
Auburn University
Yale University
Worcester Polytechnic Institute
Washington State University
Stanford University
University of Leipzig
Universidade da Beira Interior
The Institute of Cancer Research
Heidelberg University
University of Amsterdam
University of Auckland
TsingHua University
The University of Michigan
Miami University
DRURY University
Jilin University
Fudan University
Wuhan University
Sun Yat-sen University
Universite de Paris
Deemed University
Auckland University
The University of Tokyo
Korea University
- A 61603 hydrobromide
Catalog No.:BCC6912
CAS No.:107756-30-9
- Zafirlukast
Catalog No.:BCC4881
CAS No.:107753-78-6
- Methyl 7beta,15-dihydroxydehydroabietate
Catalog No.:BCN7270
CAS No.:107752-10-3
- Epleremone
Catalog No.:BCC3776
CAS No.:107724-20-9
- MDL 11,939
Catalog No.:BCC6822
CAS No.:107703-78-6
- beta-Lipoic acid
Catalog No.:BCC9198
CAS No.:6992-30-9
- Merucathine
Catalog No.:BCN1782
CAS No.:107673-74-5
- Bulleyaconitine A
Catalog No.:BCN1210
CAS No.:107668-79-1
- Merucathinone
Catalog No.:BCN1783
CAS No.:107638-80-2
- Erycibelline
Catalog No.:BCN1876
CAS No.:107633-95-4
- Dehydroformouregine
Catalog No.:BCN4054
CAS No.:107633-69-2
- PF 998425
Catalog No.:BCC7811
CAS No.:1076225-27-8
- 3,4-Dihydroxybenzenepropanoic acid
Catalog No.:BCN8500
CAS No.:1078-61-1
- PF 04418948
Catalog No.:BCC6299
CAS No.:1078166-57-0
- Exemestane
Catalog No.:BCC1061
CAS No.:107868-30-4
- Quinovin
Catalog No.:BCN5878
CAS No.:107870-05-3
- Dehydrodiconiferyl alcohol 4-O-beta-D-glucopyranoside
Catalog No.:BCN7707
CAS No.:107870-88-2
- Japonicones D
Catalog No.:BCN3614
CAS No.:1078711-42-8
- Isoeleutherin
Catalog No.:BCN8315
CAS No.:1078723-14-4
- Ganodermanondiol
Catalog No.:BCN5879
CAS No.:107900-76-5
- Sibiricose A5
Catalog No.:BCN2785
CAS No.:107912-97-0
- 9,9-Bis(4-amino-3-methylphenyl)fluorene
Catalog No.:BCC8794
CAS No.:107934-60-1
- Myricananin A
Catalog No.:BCN5880
CAS No.:1079941-35-7
- 2-(Dimethylamino)ethanol
Catalog No.:BCN1798
CAS No.:108-01-0
Triterpenoids from Roots and Stems of Kadsura coccinea.[Pubmed:17345419]
Planta Med. 1986 Dec;(6):492-3.
24-Methylenecycloartenone ( 1), kadsuric acid ( 2) and a new triterpenoid acid named Coccinic acid ( 3A) were isolated from the ether soluble fraction of the dried roots and stems of KADSURA COCCINEA.
Cytotoxic and potential anticancer constituents from the stems of Schisandra pubescens.[Pubmed:23883077]
Pharm Biol. 2013 Sep;51(9):1204-7.
CONTEXT: The diethyl ether extract of the stems of Schisandra pubescens Hemsl. et Wils. (Schisandraceae) was found to exhibit cytotoxic activity in vitro. However, investigations of the bioactive constituents of this plant have been very limited. OBJECTIVE: Elucidation of the cytotoxic constituents of S. pubescens was performed. METHODS: Repeated silica gel column chromatography and preparative TLC were used for the chemical investigation of the diethyl ether extract of S. pubescens stems. All isolates were evaluated for their in vitro cytotoxicity against A549, PC-3, KB and KBvin human cancer cell lines. RESULTS: Nine known compounds were obtained, including four lignans, epischisandrone (1), tigloylgomisin P (2), cagayanone (3) and (-)-gomisin L(2) (4), together with five triterpenoids, micranoic acid B (5), lancifodilactone H (6), Coccinic acid (7), schisanlactone B (8) and anwuweizonic acid (9). Compounds 2-6 and 8 showed moderate to marginal cytotoxicity, with GI(5)(0) values of 11.83-35.65 muM. CONCLUSION: The isolation of 1-9 from S. pubescens and the cytotoxicities of 3-6 are first reported. Compounds 2-6 and 8 could be the active principles responsible for the anticancer effects of S. pubescens.
