Boeravinone E

CAS# 137787-00-9

Boeravinone E

Catalog No. BCN4083----Order now to get a substantial discount!

Product Name & Size Price Stock
Boeravinone E:5mg Please Inquire In Stock
Boeravinone E:10mg Please Inquire In Stock
Boeravinone E:20mg Please Inquire In Stock
Boeravinone E:50mg Please Inquire In Stock

Quality Control of Boeravinone E

Number of papers citing our products

Chemical structure

Boeravinone E

3D structure

Chemical Properties of Boeravinone E

Cas No. 137787-00-9 SDF Download SDF
PubChem ID 11537197 Appearance Powder
Formula C17H12O7 M.Wt 328.3
Type of Compound Flavonoids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name 3,6,9,11-tetrahydroxy-10-methyl-6H-chromeno[3,4-b]chromen-12-one
SMILES CC1=C(C=C2C(=C1O)C(=O)C3=C(O2)C(OC4=C3C=CC(=C4)O)O)O
Standard InChIKey NCWLTPKGFNPAMP-UHFFFAOYSA-N
Standard InChI InChI=1S/C17H12O7/c1-6-9(19)5-11-13(14(6)20)15(21)12-8-3-2-7(18)4-10(8)24-17(22)16(12)23-11/h2-5,17-20,22H,1H3
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Boeravinone E

The herbs of Mirabilis jalapa

Biological Activity of Boeravinone E

Description1. Boeravinone E exhibits spasmolytic activity.

Boeravinone E Dilution Calculator

Concentration (start)
x
Volume (start)
=
Concentration (final)
x
Volume (final)
 
 
 
C1
V1
C2
V2

calculate

Boeravinone E Molarity Calculator

Mass
=
Concentration
x
Volume
x
MW*
 
 
 
g/mol

calculate

Preparing Stock Solutions of Boeravinone E

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 3.046 mL 15.23 mL 30.4599 mL 60.9199 mL 76.1499 mL
5 mM 0.6092 mL 3.046 mL 6.092 mL 12.184 mL 15.23 mL
10 mM 0.3046 mL 1.523 mL 3.046 mL 6.092 mL 7.615 mL
50 mM 0.0609 mL 0.3046 mL 0.6092 mL 1.2184 mL 1.523 mL
100 mM 0.0305 mL 0.1523 mL 0.3046 mL 0.6092 mL 0.7615 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

Organizitions Citing Our Products recently

 
 
 

Calcutta University

University of Minnesota

University of Maryland School of Medicine

University of Illinois at Chicago

The Ohio State University

University of Zurich

Harvard University

Colorado State University

Auburn University

Yale University

Worcester Polytechnic Institute

Washington State University

Stanford University

University of Leipzig

Universidade da Beira Interior

The Institute of Cancer Research

Heidelberg University

University of Amsterdam

University of Auckland
TsingHua University
TsingHua University
The University of Michigan
The University of Michigan
Miami University
Miami University
DRURY University
DRURY University
Jilin University
Jilin University
Fudan University
Fudan University
Wuhan University
Wuhan University
Sun Yat-sen University
Sun Yat-sen University
Universite de Paris
Universite de Paris
Deemed University
Deemed University
Auckland University
Auckland University
The University of Tokyo
The University of Tokyo
Korea University
Korea University
Featured Products
New Products
 

References on Boeravinone E

A beta-secretase (BACE1)-inhibiting C-methylrotenoid induced by yeast elicitation in Abronia nana suspension cultures.[Pubmed:24557951]

Appl Biochem Biotechnol. 2014 Apr;172(7):3529-37.

Suspension cultures of Abronia nana were established to produce C-methylisoflavones. Treatment of the A. nana cultures with yeast elicitor induced Boeravinone E (1), with maximum induction at 24 h after elicitor treatment. Of the biotic and abiotic elicitors tested, yeast extract gave the strongest induction of 1. The IC50 value of 1 against beta-secretase (beta-amyloid cleaving enzyme-1) was 5.57 muM. Other proteases such as trypsin, chymotrypsin, and elastase were not inhibited by concentrations up to 1.0 mM, indicating that inhibition of beta-secretase was specific. 1 was noncompetitive in Dixon plot, and Ki value was 3.79 muM.

Isolation of new rotenoids from Boerhaavia diffusa and evaluation of their effect on intestinal motility.[Pubmed:16254824]

Planta Med. 2005 Oct;71(10):928-32.

A bioassay-guided separation of a methanolic extract obtained from the roots of Boerhaavia diffusa L. (Nyctaginaceae) allowed us to isolate five compounds belonging to the class of rotenoids: the known boeravinone D ( 1), Boeravinone E ( 2), compound 5 and two novel compounds that we have named boeravinone G ( 3) and boeravinone H ( 4). The structures of the new molecules have been determined on the basis of their HR-EI-MS, (1)H- and (13)C-NMR and 2D-NMR (HMQC, HMBC) data. All the isolated rotenoids have been evaluated for their effect on intestinal motility in vitro. Three of them (boeravinone G, Boeravinone E and compound 5) exhibited spasmolytic activity. Preliminary structure-activity relationships have been established highlighting the effect of substitutions on rings B and D.

Keywords:

Boeravinone E,137787-00-9,Natural Products, buy Boeravinone E , Boeravinone E supplier , purchase Boeravinone E , Boeravinone E cost , Boeravinone E manufacturer , order Boeravinone E , high purity Boeravinone E

Online Inquiry for:

      Fill out the information below

      • Size:Qty: - +

      * Required Fields

                                      Result: