Bisabolone oxide A

CAS# 22567-38-0

Bisabolone oxide A

Catalog No. BCN9091----Order now to get a substantial discount!

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Bisabolone oxide A: 5mg $374 In Stock
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Chemical structure

Bisabolone oxide A

3D structure

Chemical Properties of Bisabolone oxide A

Cas No. 22567-38-0 SDF Download SDF
PubChem ID 90807 Appearance Powder
Formula C15H24O2 M.Wt 236.35
Type of Compound Sesquiterpenoids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name 2,2,6-trimethyl-6-(4-methylcyclohex-3-en-1-yl)oxan-3-one
SMILES CC1=CCC(CC1)C2(CCC(=O)C(O2)(C)C)C
Standard InChIKey MJWZYBQLHJQQJJ-UHFFFAOYSA-N
Standard InChI InChI=1S/C15H24O2/c1-11-5-7-12(8-6-11)15(4)10-9-13(16)14(2,3)17-15/h5,12H,6-10H2,1-4H3
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Bisabolone oxide A Dilution Calculator

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Bisabolone oxide A Molarity Calculator

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Preparing Stock Solutions of Bisabolone oxide A

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 4.231 mL 21.1551 mL 42.3101 mL 84.6203 mL 105.7753 mL
5 mM 0.8462 mL 4.231 mL 8.462 mL 16.9241 mL 21.1551 mL
10 mM 0.4231 mL 2.1155 mL 4.231 mL 8.462 mL 10.5775 mL
50 mM 0.0846 mL 0.4231 mL 0.8462 mL 1.6924 mL 2.1155 mL
100 mM 0.0423 mL 0.2116 mL 0.4231 mL 0.8462 mL 1.0578 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Bisabolone oxide A

Chemical composition and biological activities of an essential oil from the aerial parts of Artemisia Gmelinii weber ex Stechm.[Pubmed:31177847]

Nat Prod Res. 2019 Jun 7:1-4.

The aerial parts of Artemisia gmelinii Weber ex Stechm were collected from the northeast of China. The essential oil was obtained by hydrodistillation and analysed by GC-MS. A set of 66 compounds were identified representing 99.1% of the oil composition. The major compounds in the oil were cyclobutaneethanol, endo-borneol, germacrene D, eucalyptol, selin-6-en-4alpha-ol, Bisabolone oxide A, caryophyllene and terpinen-4-ol. Moreover, the essential oil was evaluated for its antioxidant, antidiabetic, and anticholinesterase activities in vitro. Additionally, the antioxidant potential of the oil was evaluated using DPPH and ABTS assays. The oil showed good antidiabetic activity with an IC50 of 63.2 microg/mL, which was similar to that of the positive control acarbose, and weak anticholinesterase activities. These findings demonstrated that the essential oil of Artemisia gmelinii may be a good natural antidiabetic.

Chemo-Diversity and Antiradical Potential of Twelve Matricaria chamomilla L. Populations from Iran: Proof of Ecological Effects.[Pubmed:30987223]

Molecules. 2019 Apr 3;24(7). pii: molecules24071315.

Matricaria chamomilla L. is a popular medicinal herb that is used for healing various diseases and is widely distributed worldwide in temperate climate zones, and even in the subtropical climate of Southern and Western Iran. This study was aimed at comparing the volatile oil constituents, along with antiradical potential and HPLC analysis of methanolic extracts from twelve plant samples growing in Iran. The present research was carried out for the first time on these populations. Among seventeen identified volatile chemicals evaluated by GC/MS and GC/FID, representing 92.73-97.71% of the total oils, alpha-Bisabolone oxide A (45.64-65.41%) was the major constituent, except in case of "Sarableh" as a new chemotype, where (E)- and (Z)-gamma-bisabolene (42.76 and 40.08%, respectively) were the predominant components. Oxygenated sesquiterpenes (53.31-74.52%) were the most abundant compounds in the samples excluding "Sarableh" with 91.3% sesquiterpene hydrocarbons. "Sarableh" also exerted the most potent antioxidant capacity with EC50 = 7.76 +/- 0.3 microg/mL and 6.51 +/- 0.63 mmol TE (Trolox((R)) equivalents)/g. In addition, populations "Lali" and "Bagh Malek" contained the highest amounts of apigenin and luteolin with 1.19 +/- 0.01 mg/g and 2.20 +/- 0.0 mg/g of plant material, respectively. Our findings depict a clear correlation between phytochemical profiles and antiradical potential of M. chamomilla and geographical factors.

Composition and Bioactivities of an (E)-beta-Farnesene Chemotype of Chamomile (Matricaria chamomilla) Essential Oil from Nepal.[Pubmed:26434140]

Nat Prod Commun. 2015 Aug;10(8):1453-7.

The essential oil of Matricaria chamomilla, collected from Nepal, was obtained by hydrodistillation and analyzed by gas chromatography-mass spectrometry. The major components in Nepalese chamomile oil were (E)-beta-famesene (42.2%), alpha-bisabolol oxide A (22.3%), (E,E)-alpha-famesene (8.3%), cis-bicycloether (5.0%), alpha-bisabolol oxide B (4.5%), and alpha-Bisabolone oxide A (4.0%). A cluster analysis based on the chemical compositions of 48 samples of chamomile oil reported in the literature has revealed seven chemotypes, and the oil from Nepal represents the (E)-beta-farnesene chemotype. The chamomile oil was screened for antimicrobial activity against Bacillus cereus, Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, Candida albicans, and Aspergillus niger, and toxicity toward MCF-7 breast tumor cells, Artemia salina, Chaoborus plumicornis, Caenorhabditis elegans, and Drosophila melanogaster.

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