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5-Methoxystrictamine

CAS# 870995-64-5

5-Methoxystrictamine

Catalog No. BCN4416----Order now to get a substantial discount!

Product Name & Size Price Stock
5-Methoxystrictamine:5mg Please Inquire In Stock
5-Methoxystrictamine:10mg Please Inquire In Stock
5-Methoxystrictamine:20mg Please Inquire In Stock
5-Methoxystrictamine:50mg Please Inquire In Stock

Quality Control of 5-Methoxystrictamine

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Chemical structure

5-Methoxystrictamine

3D structure

Chemical Properties of 5-Methoxystrictamine

Cas No. 870995-64-5 SDF Download SDF
PubChem ID 102004590 Appearance Powder
Formula C21H24N2O3 M.Wt 352.4
Type of Compound Alkaloids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name methyl (1R,10S,13E,16S)-13-ethylidene-16-methoxy-8,15-diazapentacyclo[10.5.1.01,9.02,7.010,15]octadeca-2,4,6,8-tetraene-18-carboxylate
SMILES CC=C1CN2C3CC1C(C4(C3=NC5=CC=CC=C54)CC2OC)C(=O)OC
Standard InChIKey FNXBCZCMPCVOPU-IMKKEMNLSA-N
Standard InChI InChI=1S/C21H24N2O3/c1-4-12-11-23-16-9-13(12)18(20(24)26-3)21(10-17(23)25-2)14-7-5-6-8-15(14)22-19(16)21/h4-8,13,16-18H,9-11H2,1-3H3/b12-4-/t13?,16-,17-,18?,21-/m0/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of 5-Methoxystrictamine

The herbs of Alstonia scholaris

Biological Activity of 5-Methoxystrictamine

DescriptionStandard reference

Protocol of 5-Methoxystrictamine

Structure Identification
Helvetica Chimica Acta.2005 Sep;88(9): 2508–2512.

Three New Indole Alkaloids from the Leaves of Alstonia scholaris.[Reference: WebLink]


METHODS AND RESULTS:
Three new akuamillan-type indole alkaloids, i.e., 5-Methoxystrictamine (=methyl (5β,16R,19E)-5-methoxyakuammilan-17-oate; 1), methyl (16R,19E)-1,2-dihydro-16-(hydroxymethyl)-5-oxoakuammilan-17-oate (2), and methyl (2β,16R,19E)-4,5-didehydro-1,2-dihydro-2-hydroxy-16-(hydroxymethyl)akuammilan-4-ium-17-oate chloride (3), have been isolated from the leaves of Alstonia scholaris, together with ten known compounds. Their structures were determined by spectroscopic means.
CONCLUSIONS:
None of the constituents showed significant cytotoxic activity towards WT cells.

5-Methoxystrictamine Dilution Calculator

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5-Methoxystrictamine Molarity Calculator

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Preparing Stock Solutions of 5-Methoxystrictamine

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.8377 mL 14.1884 mL 28.3768 mL 56.7537 mL 70.9421 mL
5 mM 0.5675 mL 2.8377 mL 5.6754 mL 11.3507 mL 14.1884 mL
10 mM 0.2838 mL 1.4188 mL 2.8377 mL 5.6754 mL 7.0942 mL
50 mM 0.0568 mL 0.2838 mL 0.5675 mL 1.1351 mL 1.4188 mL
100 mM 0.0284 mL 0.1419 mL 0.2838 mL 0.5675 mL 0.7094 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on 5-Methoxystrictamine

Three New Indole Alkaloids from the Leaves of Alstonia scholaris.

Helvetica Chimica Acta.2005 Sep;88(9): 2508–2512.

Three new akuamillan-type indole alkaloids, i.e., 5-Methoxystrictamine (=methyl (5β,16R,19E)-5-methoxyakuammilan-17-oate; 1), methyl (16R,19E)-1,2-dihydro-16-(hydroxymethyl)-5-oxoakuammilan-17-oate (2), and methyl (2β,16R,19E)-4,5-didehydro-1,2-dihydro-2-hydroxy-16-(hydroxymethyl)akuammilan-4-ium-17-oate chloride (3), have been isolated from the leaves of Alstonia scholaris, together with ten known compounds. Their structures were determined by spectroscopic means. None of the constituents showed significant cytotoxic activity towards WT cells.

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