Hot Products

Hot products from BioCrick which is a professional high-purity natural products manufacturer are well known to scientists around the world because of their high purity and stability. Each product is a chemical compound or substance produced by a living organism—that is, found in nature. In the broadest sense, natural products include any substance produced by life.Natural products remain the best sources of drugs and drug leads, and this remains true today despite the fact that many pharmaceutical companies have deemphasized natural products research in favor of HTP screening of combinatorial libraries during the past 2 decades. From 1940s to date, 131 (74.8%) out of 175 small molecule anticancer drugs are natural product-based/inspired, with 85 (48.6%) being either natural products or derived therefrom. From 1981 to date, 79 (80%) out of 99 small molecule anticancer drugs are natural product-based/inspired, with 53 (53%) being either natural products or derived therefrom. Among the 20 approved small molecule New Chemical Entities (NCEs) in 2010, a half of them are natural products.

Hot products from the professional high-purity natural products manufacturer

Cat.No. Product Name
BCN1816 Tetramethylammonium
1. Tetramethylammonium ion has limited toxicity of dermal exposure, but fatal effects can be introduced by pre-treatment with hydroxide ion.
BCN1818 Trichosanatine
1. Trichosanatine and squamosamide, as potential candidates as lead compounds for further study in drug development process with the PP2A- α protein. 2. Trichosanatine can alleviate oxidized low-density lipoprotein induced endothelial cells injury via inhibiting the LOX-1/p38 MAPK pathway.
BCN1819 Trimethylamine oxide
1. Trimethylamine oxide has a thermo-protective role in these cells, thus eliminating the need for a heat shock response. 2. Trimethylamine oxide can stimulate both the anaerobic growth rate and the growth yield of Proteus NTHC 153 by serving as a terminal electron acceptor in an oxidative phosphorylation process.
BCN1821 Aburatubolactam A
1. Aburatubolactam A is an inhibitor of superoxide anion generation. 2. Aburatubolactam A has demonstrated cytotoxic activity against P388 murine leukemia cell lines (IC50 = 26 ug/mL) and inhibits TPA-induced superoxide anion generation by human neutrophils; enhanced levels of superoxide anion is thought to be closely related to inflammation, cancer, and aging.
BCN1822 Aflastatin A
1. Aflastatin A is a specific inhibitor of aflatoxin production by Aspergillus parasiticus, inhibits a very early step in aflatoxin biosynthesis prior to the transcription of aflR and can influence glucose metabolism in the fungus. 2. Aflastatin A inhibits an early step in melanin production, which suppresses the expression of PKS1. 3. Aflastatin A exhibits antimicrobial activity against some bacteria, yeasts and fungi. 4. Aflastatin A has antitumor activity.
BCN1823 Altamycin A
1. Altamycin A is a kind of antibiotic.
BCN1824 Amycomycin
1. Amycomycin is active against gram-positive bacteria , it is useful as an antibiotic.
BCN1825 Antibiotic 2158
1. Antibiotic 2158 is a PAF synthesis inhibitor.